Collagenase 3 is a target of Cbfa1, a transcription factor of the runt gene family involved in bone formation.
about
AP-1 and Cbfa/runt physically interact and regulate parathyroid hormone-dependent MMP13 expression in osteoblasts through a new osteoblast-specific element 2/AP-1 composite elementThe RUNX genes: gain or loss of function in cancerRunx2- and histone deacetylase 3-mediated repression is relieved in differentiating human osteoblast cells to allow high bone sialoprotein expressionIdentification of novel genes of the bone-specific transcription factor Runx2Critical roles for collagenase-3 (Mmp13) in development of growth plate cartilage and in endochondral ossificationParathyroid hormone-Smad3 axis exerts anti-apoptotic action and augments anabolic action of transforming growth factor beta in osteoblastsParathyroid hormone activation of matrix metalloproteinase-13 transcription requires the histone acetyltransferase activity of p300 and PCAF and p300-dependent acetylation of PCAFRunx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehogGrowth defect in Grg5 null mice is associated with reduced Ihh signaling in growth platesHow matrix metalloproteinases regulate cell behavior[Immunohistochemical study on collagen I content in the gingiva in cleidocranial dysplasia].Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes.Identification of a new pebp2alphaA2 isoform from zebrafish runx2 capable of inducing osteocalcin gene expression in vitro.Specific expression of Cre recombinase in hypertrophic cartilage under the control of a BAC-Col10a1 promoter.Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development.Stemming bone loss by suppressing apoptosis.Deletion of Runx2 in Articular Chondrocytes Decelerates the Progression of DMM-Induced Osteoarthritis in Adult Mice.Dysregulation of chondrogenesis in human cleidocranial dysplasiaFactor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormones.Osteoblast apoptosis and bone turnover.High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage.O45-regulation of osteoblast differentiation and ECM remodeling by Bmp2/4 in vitro.YAP regulates the expression of Hoxa1 and Hoxc13 in mouse and human oral and skin epithelial tissuesMatrix metalloproteinase 13 (MMP13) is a direct target of osteoblast-specific transcription factor osterix (Osx) in osteoblasts.Transcriptional dysregulation in skeletal malformation syndromes.Craniosynostosis-associated gene nell-1 is regulated by runx2.Characterization of the human ADAMTS-5 (aggrecanase-2) gene promoter.Runx2, a multifunctional transcription factor in skeletal development.IKKα/CHUK regulates extracellular matrix remodeling independent of its kinase activity to facilitate articular chondrocyte differentiation.Identification of putative target genes of the transcription factor RUNX2.Revisiting the role of retinoid signaling in skeletal development.Proteases involved in cartilage matrix degradation in osteoarthritis.Integrin mediated adhesion of osteoblasts to connective tissue growth factor (CTGF/CCN2) induces cytoskeleton reorganization and cell differentiation.Activating enhancer binding protein 2 epsilon (AP-2ε)-deficient mice exhibit increased matrix metalloproteinase 13 expression and progressive osteoarthritis development.Matrix remodeling during endochondral ossification.The potential of signal transduction inhibitors for the treatment of arthritis: Is it all just JNK?Transcription factor ERG and joint and articular cartilage formation during mouse limb and spine skeletogenesis.A role for Runx2 in normal mammary gland and breast cancer bone metastasis.Role and function of matrix metalloproteinases in the differentiation and biological characterization of mesenchymal stem cells.Type X collagen gene regulation by Runx2 contributes directly to its hypertrophic chondrocyte-specific expression in vivo.
P2860
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P2860
Collagenase 3 is a target of Cbfa1, a transcription factor of the runt gene family involved in bone formation.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Collagenase 3 is a target of C ...... ly involved in bone formation.
@en
type
label
Collagenase 3 is a target of C ...... ly involved in bone formation.
@en
prefLabel
Collagenase 3 is a target of C ...... ly involved in bone formation.
@en
P2093
P2860
P356
P1476
Collagenase 3 is a target of C ...... ly involved in bone formation.
@en
P2093
P2860
P304
P356
10.1128/MCB.19.6.4431
P407
P577
1999-06-01T00:00:00Z