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Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in miceBindarit, an inhibitor of monocyte chemotactic protein synthesis, protects against bone loss induced by chikungunya virus infectionArthritogenic alphaviral infection perturbs osteoblast function and triggers pathologic bone lossThe DNA helicase recql4 is required for normal osteoblast expansion and osteosarcoma formationCoupling Signals between the Osteoclast and Osteoblast: How are Messages Transmitted between These Temporary Visitors to the Bone Surface?Quantifying the osteocyte network in the human skeletonCiliary neurotrophic factor inhibits bone formation and plays a sex-specific role in bone growth and remodelingWnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in miceDissociation of bone resorption and bone formation in adult mice with a non-functional V-ATPase in osteoclasts leads to increased bone strengthTissue inhibitor of metalloproteinase-3 (TIMP-3) regulates hematopoiesis and bone formation in vivo.Skeletal recovery after weaning does not require PTHrP.Vaginally administered PEGylated LIF antagonist blocked embryo implantation and eliminated non-target effects on bone in mice.Strain-dependent differences in bone development, myeloid hyperplasia, morbidity and mortality in ptpn2-deficient mice.Gsα enhances commitment of mesenchymal progenitors to the osteoblast lineage but restrains osteoblast differentiation in mice.Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance.An ethyl-nitrosourea-induced point mutation in phex causes exon skipping, x-linked hypophosphatemia, and rickets.Osteoclast-derived activity in the coupling of bone formation to resorption.Loss of Gsα in the Postnatal Skeleton Leads to Low Bone Mass and a Blunted Response to Anabolic Parathyroid Hormone TherapyDelayed development of specific thyroid hormone-regulated events in transthyretin null mice.gp130 signaling in bone cell biology: multiple roles revealed by analysis of genetically altered mice.Molecular mechanisms in coupling of bone formation to resorption.Coupling the activities of bone formation and resorption: a multitude of signals within the basic multicellular unitWhat is the true nature of the osteoblastic hematopoietic stem cell niche?High dose dietary vitamin D3 increases bone mass and strength in mice.Leukemia inhibitory factor: a paracrine mediator of bone metabolism.Intercellular cross-talk among bone cells: new factors and pathways.Cell-cell signaling: broadening our view of the basic multicellular unit.Implications of osteoblast-osteoclast interactions in the management of osteoporosis by antiresorptive agents denosumab and odanacatib.Regulation of cortical and trabecular bone mass by communication between osteoblasts, osteocytes and osteoclasts.Osteoimmunology: oncostatin M as a pleiotropic regulator of bone formation and resorption in health and disease.Arthritogenic alphaviruses: new insights into arthritis and bone pathology.RANKL/OPG; Critical role in bone physiology.Sustained RANKL response to parathyroid hormone in oncostatin M receptor-deficient osteoblasts converts anabolic treatment to a catabolic effect in vivo.Cardiotrophin-like cytokine factor 1 (CLCF1) and neuropoietin (NP) signalling and their roles in development, adulthood, cancer and degenerative disorders.Cell-specific paracrine actions of IL-6 family cytokines from bone, marrow and muscle that control bone formation and resorption.Myokines (muscle-derived cytokines and chemokines) including ciliary neurotrophic factor (CNTF) inhibit osteoblast differentiation.Anabolic action of parathyroid hormone (PTH) does not compromise bone matrix mineral composition or maturation.EphB/ephrin-B interactions mediate human MSC attachment, migration and osteochondral differentiation.Glycoprotein130 (Gp130)/interleukin-6 (IL-6) signalling in osteoclasts promotes bone formation in periosteal and trabecular bone.RARγ is a negative regulator of osteoclastogenesis.
P50
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P50
description
hulumtuese
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հետազոտող
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Natalie A. Sims
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Natalie A. Sims
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Natalie A. Sims
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Natalie A. Sims
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Natalie A. Sims
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Natalie A. Sims
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Natalie A. Sims
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Natalie A. Sims
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Natalie A. Sims
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Natalie A. Sims
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Natalie Sims
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Natalie A. Sims
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Natalie A. Sims
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Natalie A. Sims
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Natalie A. Sims
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Natalie A. Sims
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P1053
A-7192-2012
P106
P1153
7005365688
P21
P2798
P31
P496
0000-0003-1421-8468