In Saccharomyces cerevisae, feedback inhibition of homocitrate synthase isoenzymes by lysine modulates the activation of LYS gene expression by Lys14p.
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Genome-wide analysis of tRNA charging and activation of the eIF2 kinase Gcn2pThe Expanding Landscape of Moonlighting Proteins in YeastsMechanism of Substrate Recognition and Insight into Feedback Inhibition of Homocitrate Synthase from Thermus thermophilusStructural Basis for L-Lysine Feedback Inhibition of Homocitrate SynthaseThe proper folding of a long C-terminal segment of the yeast Lys14p regulator is required for activation of LYS genes in response to the metabolic effector.Oxidative stress-activated zinc cluster protein Stb5 has dual activator/repressor functions required for pentose phosphate pathway regulation and NADPH production.Yeast zinc cluster proteins Dal81 and Uga3 cooperate by targeting common coactivators for transcriptional activation of γ-aminobutyrate responsive genes.Overproduction of threonine aldolase circumvents the biosynthetic role of pyruvate decarboxylase in glucose-limited chemostat cultures of Saccharomyces cerevisiae.A moonlighting metabolic protein influences repair at DNA double-stranded breaks.Heptahelical protein PQLC2 is a lysosomal cationic amino acid exporter underlying the action of cysteamine in cystinosis therapyTranscriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeastComprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae.Phenotypic analysis of genes encoding yeast zinc cluster proteins.Characterization of bacterial homocitrate synthase involved in lysine biosynthesis.Evaluation of lysine biosynthesis as an antifungal drug target: biochemical characterization of Aspergillus fumigatus homocitrate synthase and virulence studiesLoss of compartmentalization causes misregulation of lysine biosynthesis in peroxisome-deficient yeast cells.Novel distal eQTL analysis demonstrates effect of population genetic architecture on detecting and interpreting associationsSynthetic cooperation in engineered yeast populations.Regulation of amino acid, nucleotide, and phosphate metabolism in Saccharomyces cerevisiae.A fungal family of transcriptional regulators: the zinc cluster proteinsSpatial self-organization favors heterotypic cooperation over cheating.Convergent strategies in biosynthesis.Contribution of the C-terminal region within the catalytic core domain of HIV-1 integrase to yeast lethality, chromatin binding and viral replication.Metabolic engineering of Saccharomyces cerevisiae for production of novel cyanophycins with an extended range of constituent amino acids.Homocitrate synthase connects amino acid metabolism to chromatin functions through Esa1 and DNA damage.A lysine accumulation phenotype of ScIpk2Delta mutant yeast is rescued by Solanum tuberosum inositol phosphate multikinase.Establishment of cyanophycin biosynthesis in Pichia pastoris and optimization by use of engineered cyanophycin synthetases.Large-scale functional analysis of the roles of phosphorylation in yeast metabolic pathways.Regulatory mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae. I. Kinetic studies.Inactivation of homocitrate synthase causes lysine auxotrophy in copper/zinc-containing superoxide dismutase-deficient yeast Schizosaccharomyces pombe.Identification of differentially expressed genes in yeast Saccharomyces cerevisiae cells with inactivated Mmf1p and Hmf1p, members of proteins family YERO57c/YJGF.
P2860
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P2860
In Saccharomyces cerevisae, feedback inhibition of homocitrate synthase isoenzymes by lysine modulates the activation of LYS gene expression by Lys14p.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
In Saccharomyces cerevisae, fe ...... LYS gene expression by Lys14p.
@en
type
label
In Saccharomyces cerevisae, fe ...... LYS gene expression by Lys14p.
@en
prefLabel
In Saccharomyces cerevisae, fe ...... LYS gene expression by Lys14p.
@en
P2093
P2860
P1433
P1476
In Saccharomyces cerevisae, fe ...... LYS gene expression by Lys14p.
@en
P2093
P2860
P304
P356
10.1046/J.1432-1327.1999.00262.X
P407
P577
1999-04-01T00:00:00Z