Inositol 1,4,5-trisphosphate receptor down-regulation is activated directly by inositol 1,4,5-trisphosphate binding. Studies with binding-defective mutant receptors.
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IP3 receptor-mediated Ca2+ release in naive CD4 T cells dictates their cytokine programInositol 1,4,5-trisphosphate receptor ubiquitination is mediated by mammalian Ubc7, a component of the endoplasmic reticulum-associated degradation pathway, and is inhibited by chelation of intracellular Zn2+IRBIT, a novel inositol 1,4,5-trisphosphate (IP3) receptor-binding protein, is released from the IP3 receptor upon IP3 binding to the receptorInvolvement of the p97-Ufd1-Npl4 complex in the regulated endoplasmic reticulum-associated degradation of inositol 1,4,5-trisphosphate receptorsInositol 1,4,5-trisphosphate receptor 1 degradation in mouse eggs and impact on [Ca2+]i oscillationsCalcium at fertilization and in early developmentEffect of M-phase kinase phosphorylations on type 1 inositol 1,4,5-trisphosphate receptor-mediated Ca2+ responses in mouse eggsLigand binding directly stimulates ubiquitination of the inositol 1, 4,5-trisphosphate receptor.The role of Ca2+ in triggering inositol 1,4,5-trisphosphate receptor ubiquitination.The contribution of serine residues 1588 and 1755 to phosphorylation of the type I inositol 1,4,5-trisphosphate receptor by PKA and PKG.Inhibition of the inositol trisphosphate receptor of mouse eggs and A7r5 cells by KN-93 via a mechanism unrelated to Ca2+/calmodulin-dependent protein kinase II antagonism.Down-regulation of types I, II and III inositol 1,4,5-trisphosphate receptors is mediated by the ubiquitin/proteasome pathwaySperm factor induces intracellular free calcium oscillations by stimulating the phosphoinositide pathway.Ubiquitination and proteasomal degradation of endogenous and exogenous inositol 1,4,5-trisphosphate receptors in alpha T3-1 anterior pituitary cells.Fertilization 2: Polyspermic Fertilization.Mechanism of proteasomal degradation of inositol trisphosphate receptors in CHO-K1 cells.The inhibition of [³H] inositol 1,4,5-trisphosphate binding by Ca²⁺ is modified after long-term ethanol treatment and ethanol withdrawal.Isoforms of the inositol 1,4,5-trisphosphate receptor are expressed in bovine oocytes and ovaries: the type-1 isoform is down-regulated by fertilization and by injection of adenophostin A.
P2860
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P2860
Inositol 1,4,5-trisphosphate receptor down-regulation is activated directly by inositol 1,4,5-trisphosphate binding. Studies with binding-defective mutant receptors.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Inositol 1,4,5-trisphosphate r ...... ng-defective mutant receptors.
@en
type
label
Inositol 1,4,5-trisphosphate r ...... ng-defective mutant receptors.
@en
prefLabel
Inositol 1,4,5-trisphosphate r ...... ng-defective mutant receptors.
@en
P2093
P2860
P356
P1476
Inositol 1,4,5-trisphosphate r ...... ng-defective mutant receptors.
@en
P2093
Furuichi T
Mikoshiba K
Wojcikiewicz RJ
P2860
P304
P356
10.1074/JBC.274.6.3476
P407
P577
1999-02-01T00:00:00Z