Molecular insights into the ligand-controlled organization of the SAM-I riboswitch.
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Fluorescence-Based Strategies to Investigate the Structure and Dynamics of Aptamer-Ligand ComplexesLinking aptamer-ligand binding and expression platform folding in riboswitches: prospects for mechanistic modeling and designMolecular recognition and function of riboswitchesThe impact of a ligand binding on strand migration in the SAM-I riboswitchMolecular sensing by the aptamer domain of the FMN riboswitch: a general model for ligand binding by conformational selectionYbxF and YlxQ are bacterial homologs of L7Ae and bind K-turns but not K-loopsStructural basis for diversity in the SAM clan of riboswitchesMetabolite recognition principles and molecular mechanisms underlying riboswitch functionCommon themes and differences in SAM recognition among SAM riboswitchesStructure-guided design of fluorescent S-adenosylmethionine analogs for a high-throughput screen to target SAM-I riboswitch RNAsTuning a riboswitch response through structural extension of a pseudoknot.Hierarchy of RNA functional dynamics.Ligand binding by the tandem glycine riboswitch depends on aptamer dimerization but not double ligand occupancyCyclic di-GMP riboswitch-regulated type IV pili contribute to aggregation of Clostridium difficile.Constitutive regulatory activity of an evolutionarily excluded riboswitch variant.A kissing loop is important for btuB riboswitch ligand sensing and regulatory control.Allosteric tertiary interactions preorganize the c-di-GMP riboswitch and accelerate ligand binding.Basis for ligand discrimination between ON and OFF state riboswitch conformations: the case of the SAM-I riboswitch.Biophysical Approaches to Bacterial Gene Regulation by Riboswitches.A Highly Coupled Network of Tertiary Interactions in the SAM-I Riboswitch and Their Role in Regulatory Tuning.Tuning RNA Flexibility with Helix Length and Junction Sequence.The expression platform and the aptamer: cooperativity between Mg2+ and ligand in the SAM-I riboswitch.Conformational heterogeneity of the SAM-I riboswitch transcriptional ON state: a chaperone-like role for S-adenosyl methionine.Microfluidic screening of electrophoretic mobility shifts elucidates riboswitch binding functionBiomolecular dynamics: order-disorder transitions and energy landscapesSingle-molecule studies of the lysine riboswitch reveal effector-dependent conformational dynamics of the aptamer domain.Product feedback regulation implicated in translational control of the Trypanosoma brucei S-adenosylmethionine decarboxylase regulatory subunit prozymeMg(2+)-induced conformational changes in the btuB riboswitch from E. coliTb3+-Cleavage Assays Reveal Specific Mg2+ Binding Sites Necessary to Pre-fold the btuB Riboswitch for AdoCbl Binding.Themes and variations in riboswitch structure and function.Single-molecule studies of riboswitch folding.Role of lysine binding residues in the global folding of the lysC riboswitch.Ligand-detected relaxation dispersion NMR spectroscopy: dynamics of preQ1-RNA binding.Sequence elements distal to the ligand binding pocket modulate the efficiency of a synthetic riboswitch.An integrated perspective on RNA aptamer ligand-recognition models: clearing muddy waters.Single-molecule chemical denaturation of riboswitches.Direct structural analysis of modified RNA by fluorescent in-line probingTranscriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation.A two-stage mechanism of viral RNA compaction revealed by single molecule fluorescence.RNA Structural Modules Control the Rate and Pathway of RNA Folding and Assembly.
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Molecular insights into the ligand-controlled organization of the SAM-I riboswitch.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Molecular insights into the ligand-controlled organization of the SAM-I riboswitch.
@en
type
label
Molecular insights into the ligand-controlled organization of the SAM-I riboswitch.
@en
prefLabel
Molecular insights into the ligand-controlled organization of the SAM-I riboswitch.
@en
P2093
P2860
P356
P1476
Molecular insights into the ligand-controlled organization of the SAM-I riboswitch.
@en
P2093
Anne-Marie Dussault
Benoit Heppell
Daniel A Lafontaine
Eric Ennifar
J Carlos Penedo
Jérôme Mulhbacher
Simon Blouin
P2860
P2888
P304
P356
10.1038/NCHEMBIO.563
P577
2011-05-01T00:00:00Z
P6179
1014069253