Triplex DNA-mediated downregulation of Ets2 expression results in growth inhibition and apoptosis in human prostate cancer cells.
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The function of APC/CCdh1 in cell cycle and beyondGrowth inhibition and apoptosis induced by daunomycin-conjugated triplex-forming oligonucleotides targeting the c-myc gene in prostate cancer cellsDisruption of Higher Order DNA Structures in Friedreich's Ataxia (GAA)n Repeats by PNA or LNA TargetingExploring the cellular activity of camptothecin-triple-helix-forming oligonucleotide conjugates.Changes in the transcriptional profile in response to overexpression of the osteopontin-c splice isoform in ovarian (OvCar-3) and prostate (PC-3) cancer cell lines.Novel GC-rich DNA-binding compound produced by a genetically engineered mutant of the mithramycin producer Streptomyces argillaceus exhibits improved transcriptional repressor activity: implications for cancer therapy.Potential contribution of SIM2 and ETS2 functional polymorphisms in Down syndrome associated malignancies.Ets-2 regulates cell apoptosis via the Akt pathway, through the regulation of urothelial cancer associated 1, a long non-coding RNA, in bladder cancer cells.The paperclip triplex: understanding the role of apex residues in tight turns.Cellular and molecular consequences of peroxisome proliferator-activated receptor-gamma activation in ovarian cancer cells.Ets2 maintains hTERT gene expression and breast cancer cell proliferation by interacting with c-Myc.PDEF is a negative regulator of colon cancer cell growth and migrationTumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome.Naturally extended CT . AG repeats increase H-DNA structures and promoter activity in the smooth muscle myosin light chain kinase geneModifying metabolically sensitive histone marks by inhibiting glutamine metabolism affects gene expression and alters cancer cell phenotype.Purine twisted-intercalating nucleic acids: a new class of anti-gene molecules resistant to potassium-induced aggregation.ETS2 and Twist1 promote invasiveness of Helicobacter pylori-infected gastric cancer cells by inducing Siah2ETS transcription factors: oncogenes and tumor suppressor genes as therapeutic targets for prostate cancer.Spi-1 and Fli-1 directly activate common target genes involved in ribosome biogenesis in Friend erythroleukemic cells.Promoter-specific transcriptional interference and c-myc gene silencing by siRNAs in human cells.Calorimetric and spectroscopic studies of aminoglycoside binding to AT-rich DNA triple helices.Potential in vivo roles of nucleic acid triple-helices.Recent patents on therapeutic applications of the transcription factor decoy approach.Drug-induced hyperploidy stimulates an antitumor NK cell response mediated by NKG2D and DNAM-1 receptors.Ets-2 and p160 proteins collaborate to regulate c-Myc in endocrine resistant breast cancer.Reduced expression and tumor suppressor function of the ETS transcription factor ESE-3 in prostate cancer.ETS-1 and ETS-2 are upregulated in a transgenic mouse model of pigmented ocular neoplasm.Ets2 knockdown inhibits tumorigenesis in esophageal squamous cell carcinoma in vivo and in vitro.ESE-1/ELF3 mRNA expression associates with poor survival outcomes in HER2+ breast cancer patients and is critical for tumorigenesis in HER2+ breast cancer cells.ERG is specifically associated with ETS-2 and ETV-4, but not with ETS-1, in prostate cancer.Identification of genes containing expanded purine repeats in the human genome and their apparent protective role against cancer.Purine- and pyrimidine-triple helix forming oligonucleotides recognize qualitatively different target sites at the ribosomal DNA locus.
P2860
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P2860
Triplex DNA-mediated downregulation of Ets2 expression results in growth inhibition and apoptosis in human prostate cancer cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
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2004年學術文章
@zh-hant
name
Triplex DNA-mediated downregul ...... n human prostate cancer cells.
@en
type
label
Triplex DNA-mediated downregul ...... n human prostate cancer cells.
@en
prefLabel
Triplex DNA-mediated downregul ...... n human prostate cancer cells.
@en
P2093
P2860
P356
P1476
Triplex DNA-mediated downregul ...... n human prostate cancer cells.
@en
P2093
Alessandra Valentini
Carlo V Catapano
Dennis K Watson
Franco Cavalli
Giuseppina M Carbone
Sara Napoli
P2860
P304
P356
10.1093/NAR/GKH744
P407
P577
2004-08-16T00:00:00Z