Single amino acid substitutions in one Ca2+ binding site of uvomorulin abolish the adhesive function.
about
Protocadherins: a large family of cadherin-related molecules in central nervous systemExpression of M-cadherin, a member of the cadherin multigene family, correlates with differentiation of skeletal muscle cellsRegulation of connexin 43-mediated gap junctional intercellular communication by Ca2+ in mouse epidermal cells is controlled by E-cadherinDirect Ca2+-dependent heterophilic interaction between desmosomal cadherins, desmoglein and desmocollin, contributes to cell-cell adhesionQuantitative analysis of cadherin-catenin-actin reorganization during development of cell-cell adhesionAlterations of E-cadherin and beta-catenin in gastric cancerIdentification and characterization of subfamily-specific signatures in a large protein superfamily by a hidden Markov model approachA new crystal structure, Ca2+ dependence and mutational analysis reveal molecular details of E-cadherin homoassociation.E-cadherin roles in animal biology: A perspective on thyroid hormone-influenceCloning of five human cadherins clarifies characteristic features of cadherin extracellular domain and provides further evidence for two structurally different types of cadherinSolution structure of the epithelial cadherin domain responsible for selective cell adhesion.Nanomechanics of the cadherin ectodomain: "canalization" by Ca2+ binding results in a new mechanical element.Allosteric cross talk between cadherin extracellular domains.Synergy between extracellular modules of vascular endothelial cadherin promotes homotypic hexameric interactions.Self-assembly of the vascular endothelial cadherin ectodomain in a Ca2+-dependent hexameric structure.Cloning and characterization of the polyhydroxybutyrate depolymerase gene of Pseudomonas stutzeri and analysis of the function of substrate-binding domains.Genomic organization and chromosomal mapping of the mouse P-cadherin geneGenomic profile analysis of diffuse-type gastric cancersIn the first extracellular domain of E-cadherin, heterophilic interactions, but not the conserved His-Ala-Val motif, are required for adhesion.Cadherin mechanics and complexation: the importance of calcium binding.A targeted mutation in the mouse E-cadherin gene results in defective preimplantation developmentT-cadherin-mediated cell growth regulation involves G2 phase arrest and requires p21(CIP1/WAF1) expressionE-cadherin gene mutations in human gastric carcinoma cell linesCovalent and density-controlled surface immobilization of E-cadherin for adhesion force spectroscopy.The E-cadherin gene (CDH1) variants T340A and L599V in gastric and colorectal cancer patients in Korea.E-cadherin gene mutations frequently occur in synovial sarcoma as a determinant of histological features.Structure-based models of cadherin-mediated cell adhesion: the evolution continues.Characterization of soluble E-cadherin as a disease marker in gastric cancer patients.Differential perturbations in the morphogenesis of anterior structures induced by overexpression of truncated XB- and N-cadherins in Xenopus embryos.The molecular organization of endothelial cell to cell junctions: differential association of plakoglobin, beta-catenin, and alpha-catenin with vascular endothelial cadherin (VE-cadherin)Intracellular domain of desmoglein 3 (pemphigus vulgaris antigen) confers adhesive function on the extracellular domain of E-cadherin without binding catenins.Adhesive but not lateral E-cadherin complexes require calcium and catenins for their formation.Dimeric states of neural- and epithelial-cadherins are distinguished by the rate of disassembly.N-Cadherin extracellular repeat 4 mediates epithelial to mesenchymal transition and increased motilityMultiple cadherin extracellular repeats mediate homophilic binding and adhesion.Mechanism of activation of the ret proto-oncogene by multiple endocrine neoplasia 2A mutationsUrinary concentrations of the soluble adhesion molecule E-cadherin and total protein in patients with bladder cancer.Cadherin 2/4 signaling via PTP1B and catenins is crucial for nucleokinesis during radial neuronal migration in the neocortexDesmocollins form a distinct subset of the cadherin family of cell adhesion molecules.Copper and calcium binding motifs in the extracellular domains of fibroblast growth factor receptors.
P2860
Q24309231-10B1DBFF-CF68-40E1-8ECD-5A12B2268864Q24562626-51618BED-10A6-4030-ABC5-B582451C1191Q24644231-38FD28F7-D573-4044-B9EE-E7863AD6BB64Q24678410-7FC91C94-A141-468D-A6C6-C99149AE9BADQ24681681-A216096E-7CC2-4CCA-989C-D9D450444A4EQ24796394-2C2DC847-E202-4E82-B738-584E4C0EFE9EQ24800415-09131B38-4C0F-4584-ADE0-6C47CF27E7D5Q27617935-86B48FED-A8FF-487E-8F9B-A294D9A3DEE5Q28079585-FFA55464-E486-437C-8607-08AEA59AFFADQ28242036-BE083DF7-C40D-45D9-8750-3F5ACE379743Q30193717-6E6134B7-D593-4B6C-9796-AD9272640304Q30427814-620D6829-82FA-4EEB-9A90-93234B990666Q30431469-E409E614-815E-4F14-A394-01AF9A8F900DQ30804229-4076FD3E-300B-4C0D-8B8D-7F98B2733841Q30957610-F0083846-13B2-4851-89B2-C9C70924806FQ31942656-1585DACA-7770-4878-868B-840BB30925F4Q33376224-837CE3B6-B472-41A2-AA59-527CC4CDB585Q33751124-8D3B6645-A81B-4E34-BAC7-721BA76181BBQ34142420-3BC391BE-6DC5-418B-A3CD-7610C32FC3C0Q34352406-E09C7F12-00CB-470F-A542-318B7FF741BFQ34743325-EC676A83-96A1-4179-AA04-56BF4D281CD9Q34811769-D078B0FD-A8DD-4001-93E9-C6D56E5AD881Q35078532-1730D9D8-0724-40DB-B206-6772F001651AQ35133556-F4DC69B5-4B13-4843-B59C-A63EC7A22216Q35360910-4857FE9E-1280-498C-89E1-CA3CFDDAAD90Q35747099-2224B693-5433-4EAD-8495-54B676FD1E17Q35854120-DCABCF66-A0E4-40EB-B167-6F1059551EC6Q36115556-A049FDD5-4FE6-42FA-8744-6A559BE49198Q36234732-60B7117D-2EFE-4EDC-A517-8541AEDDFF7FQ36235299-45C29B35-3132-416E-8B30-D9EB648E2B92Q36235402-19FF6E2C-C1E3-47DA-A34D-DBF552F67FC5Q36288279-C9046D25-418A-4F04-AE47-5F901A6C6BAAQ36316934-5E0AECA7-F8B8-46C7-80D3-DA63F4159699Q36360384-833D47BA-2AD1-40BE-9080-CC26FF5AEC5CQ36377936-174A3386-C75E-4DC5-AE8C-4C7607A72246Q36550021-2910BA9D-8EB8-4DD3-81A6-CE714C3D8EB2Q36620187-69F3CD23-22DF-4D4A-A73B-D92BE103CA3AQ37036223-974541ED-0EDE-4487-BA1A-F5D44DFC5125Q37516317-06312386-DD65-4F30-8837-78D2C4D3AE1AQ38361528-ADBBDA94-F102-4AAD-BD30-D3914EA5F489
P2860
Single amino acid substitutions in one Ca2+ binding site of uvomorulin abolish the adhesive function.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年学术文章
@wuu
1990年学术文章
@zh-cn
1990年学术文章
@zh-hans
1990年学术文章
@zh-my
1990年学术文章
@zh-sg
1990年學術文章
@yue
1990年學術文章
@zh
1990年學術文章
@zh-hant
name
Single amino acid substitution ...... abolish the adhesive function.
@en
type
label
Single amino acid substitution ...... abolish the adhesive function.
@en
prefLabel
Single amino acid substitution ...... abolish the adhesive function.
@en
P2093
P1433
P1476
Single amino acid substitution ...... abolish the adhesive function.
@en
P2093
P304
P356
10.1016/0092-8674(90)90506-A
P407
P577
1990-11-01T00:00:00Z