Early target genes of IL-12 and STAT4 signaling in th cells.
about
An integrative computational systems biology approach identifies differentially regulated dynamic transcriptome signatures which drive the initiation of human T helper cell differentiationGenomic views of STAT function in CD4+ T helper cell differentiationQuantitative proteomics reveals GIMAP family proteins 1 and 4 to be differentially regulated during human T helper cell differentiationTpl2 kinase regulates T cell interferon-gamma production and host resistance to Toxoplasma gondiiRegulatory T Cells Control Immune Responses through Their Non-Redundant Tissue Specific Features.Temporal induction pattern of STAT4 target genes defines potential for Th1 lineage-specific programmingGamma-irradiated influenza virus uniquely induces IFN-I mediated lymphocyte activation independent of the TLR7/MyD88 pathway.Allergen challenge induces Ifng dependent GTPases in the lungs as part of a Th1 transcriptome response in a murine model of allergic asthma.Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation.Quantitative proteomics analysis of the nuclear fraction of human CD4+ cells in the early phases of IL-4-induced Th2 differentiation.Cdc42-mediated MTOC polarization in dendritic cells controls targeted delivery of cytokines at the immune synapse.Decreased signal transducers and activators of transcription (STAT) protein expression in lymphatic organs during EAE development in mice.Inferring relevant control mechanisms for interleukin-12 signaling in naïve CD4+ T cells.Proprotein convertase FURIN constrains Th2 differentiation and is critical for host resistance against Toxoplasma gondii.The proprotein convertase subtilisin/kexin furinA regulates zebrafish host response against Mycobacterium marinum.Interleukin-12 drives the Th1 signaling pathway in Helicobacter pylori-infected human gastric mucosa.Proprotein convertase furin is preferentially expressed in T helper 1 cells and regulates interferon gamma.Regulation of acute graft-versus-host disease by microRNA-155.Transcriptional regulatory networks for CD4 T cell differentiation.Epigenetic regulation of IL-12-dependent T cell proliferation.Helper T-cell identity and evolution of differential transcriptomes and epigenomes.Development of proteoglycan-induced arthritis is independent of IL-17.Signal transducer and activation of transcription (STAT) 4beta, a shorter isoform of interleukin-12-induced STAT4, is preferentially activated by estrogenAn insight into molecular mechanisms of human T helper cell differentiation.From a gene-centric to whole-proteome view of differentiation of T helper cell subsets.STAT4 is critical for immunity but not for antileishmanial activity of antimonials in experimental visceral leishmaniasis.Expression of the p66Shc protein adaptor is regulated by the activator of transcription STAT4 in normal and chronic lymphocytic leukemia B cells.Enteric pathogens and gut function: Role of cytokines and STATsSignal Transducers and Activators of Transcription (STAT) family members in helminth infections.Holistic systems biology approaches to molecular mechanisms of human helper T cell differentiation to functionally distinct subsets.Therapeutic potential of STAT4 in autoimmunity.Identification of genes involved in the initiation of human Th1 or Th2 cell commitment.Cotransduction of CCL27 gene can improve the efficacy and safety of IL-12 gene therapy for cancer.Effects of microRNA-21 on the interleukin 12/signal transducer and activator of transcription 4 signaling pathway in asthmatic mice.Cerebrospinal fluid findings in multiple sclerosis patients before, during and after pregnancy.Association of STAT4 rs7574865 with susceptibility to systemic lupus erythematosus in Iranian population.CD8+ T cells in beige adipogenesis and energy homeostasis.Characterization of microsomal fraction proteome in human lymphoblasts reveals the down-regulation of galectin-1 by interleukin-12.Treatment-naïve HPV+ head and neck cancers display a T-cell-inflamed phenotype distinct from their HPV- counterparts that has implications for immunotherapy
P2860
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P2860
Early target genes of IL-12 and STAT4 signaling in th cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
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2004年學術文章
@zh-hant
name
Early target genes of IL-12 and STAT4 signaling in th cells.
@en
type
label
Early target genes of IL-12 and STAT4 signaling in th cells.
@en
prefLabel
Early target genes of IL-12 and STAT4 signaling in th cells.
@en
P2093
P1476
Early target genes of IL-12 and STAT4 signaling in th cells
@en
P2093
Joonas Scheinin
Riitta Lahesmaa
P304
P356
10.4049/JIMMUNOL.172.11.6775
P407
P50
P577
2004-06-01T00:00:00Z