Expression of the carbohydrate recognition domain of FimH and development of a competitive binding assay.
about
The tyrosine gate of the bacterial lectin FimH: a conformational analysis by NMR spectroscopy and X-ray crystallographyMutation of Tyr137 of the universal Escherichia coli fimbrial adhesin FimH relaxes the tyrosine gate prior to mannose binding.A molecular-modeling toolbox aimed at bridging the gap between medicinal chemistry and computational sciences.Structural basis for sulfation-dependent self-glycan recognition by the human immune-inhibitory receptor Siglec-82-Oxabutane as a substitute for internal monomer units of oligosaccharides to create lectin ligands.Rational design strategies for FimH antagonists: new drugs on the horizon for urinary tract infection and Crohn's disease.FimH antagonists: structure-activity and structure-property relationships for biphenyl α-D-mannopyranosides.The Conformational Variability of FimH: Which Conformation Represents the Therapeutic Target?Conformational Switch of the Bacterial Adhesin FimH in the Absence of the Regulatory Domain - Engineering a Minimalistic Allosteric System.Addressing the global need to combat multidrug resistance: carbohydrates may hold the key.Mannosylated N-aryl substituted 3-hydroxypyridine-4-ones: synthesis, hemagglutination inhibitory properties, and molecular modeling.The price of flexibility - a case study on septanoses as pyranose mimetics.Kinetic properties of carbohydrate-lectin interactions: FimH antagonists.
P2860
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P2860
Expression of the carbohydrate recognition domain of FimH and development of a competitive binding assay.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
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2010年學術文章
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name
Expression of the carbohydrate ...... f a competitive binding assay.
@en
type
label
Expression of the carbohydrate ...... f a competitive binding assay.
@en
prefLabel
Expression of the carbohydrate ...... f a competitive binding assay.
@en
P2093
P356
P1476
Expression of the carbohydrate ...... f a competitive binding assay.
@en
P2093
Beat Ernst
Oliver Schwardt
Said Rabbani
Xiaohua Jiang
P304
P356
10.1016/J.AB.2010.08.007
P407
P577
2010-08-10T00:00:00Z