The role of neurofibromin in N-Ras mediated AP-1 regulation in malignant peripheral nerve sheath tumors
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Activated Ras as a Therapeutic Target: Constraints on Directly Targeting Ras Isoforms and Wild-Type versus Mutated ProteinsMAF mediates crosstalk between Ras-MAPK and mTOR signaling in NF1.In vivo regulation of TGF-β by R-Ras2 revealed through loss of the RasGAP protein NF1.How to Target Activated Ras Proteins: Direct Inhibition vs. Induced Mislocalization.Sustained inhibition of receptor tyrosine kinases and macrophage depletion by PLX3397 and rapamycin as a potential new approach for the treatment of MPNSTs.Expression profiling of 519 kinase genes in matched malignant peripheral nerve sheath tumor/plexiform neurofibroma samples is discriminatory and identifies mitotic regulators BUB1B, PBK and NEK2 as overexpressed with transformation.Targeted inhibition of glutaminase as a potential new approach for the treatment of NF1 associated soft tissue malignancies.Targeting of AKT/ERK/CTNNB1 by DAW22 as a potential therapeutic compound for malignant peripheral nerve sheath tumor
P2860
Q27027458-8EC9C615-D5CA-41E4-8C33-7E2456F50DC4Q34022861-98124B18-CE97-4981-A8DB-3F492C919C8CQ34488339-C5C4E91C-2584-4897-AAD0-3AC41368E9C8Q37113976-B59276D6-7FDC-481C-8411-1D85164D3A48Q40804607-5F4E7DB1-7A1C-4C4C-9FE6-887777D60F38Q46083335-E32B7099-CC1F-409A-B808-48449DE7A4FEQ49367042-19933577-AB33-46BF-8E0C-988A0388D4EBQ58775869-D82C4922-D569-4249-A25F-F0E7A4639103
P2860
The role of neurofibromin in N-Ras mediated AP-1 regulation in malignant peripheral nerve sheath tumors
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2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
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2010年學術文章
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name
The role of neurofibromin in N ...... peripheral nerve sheath tumors
@en
type
label
The role of neurofibromin in N ...... peripheral nerve sheath tumors
@en
prefLabel
The role of neurofibromin in N ...... peripheral nerve sheath tumors
@en
P2093
P2860
P1476
The role of neurofibromin in N ...... peripheral nerve sheath tumors
@en
P2093
Daochun Sun
Janice M Kraniak
John J Reiners
Michael A Tainsky
Raymond R Mattingly
P2860
P2888
P304
P356
10.1007/S11010-010-0551-1
P577
2010-08-01T00:00:00Z
P6179
1029088983