ASPP2 binds Par-3 and controls the polarity and proliferation of neural progenitors during CNS development.
about
Inhibitory member of the apoptosis-stimulating proteins of the p53 family (iASPP) interacts with protein phosphatase 1 via a noncanonical binding motifThe E3 ubiquitin ligase Itch and Yap1 have antagonistic roles in the regulation of ASPP2 protein stabilityEpithelial cell polarity: a major gatekeeper against cancer?Spindle orientation in mammalian cerebral cortical developmentEchoes of a distant past: The cag pathogenicity island of Helicobacter pyloriHuntingtin Is Required for Epithelial Polarity through RAB11A-Mediated Apical Trafficking of PAR3-aPKCStructure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2ASPP2 suppresses stem cell-like characteristics and chemoresistance by inhibiting the Src/FAK/Snail axis in hepatocellular carcinoma.STAT1-induced ASPP2 transcription identifies a link between neuroinflammation, cell polarity, and tumor suppressionASPP2 suppresses squamous cell carcinoma via RelA/p65-mediated repression of p63The signaling adaptor GAB1 regulates cell polarity by acting as a PAR protein scaffold.Helicobacter pylori cytotoxin-associated gene A (CagA) subverts the apoptosis-stimulating protein of p53 (ASPP2) tumor suppressor pathway of the hostThe neural milieu of the developing choroid plexus: neural stem cells, neurons and innervation.Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene.Attenuated expression of apoptosis stimulating protein of p53-2 (ASPP2) in human acute leukemia is associated with therapy failurePhosphorylation of ASPP2 by RAS/MAPK pathway is critical for its full pro-apoptotic functionMorphological and functional aspects of progenitors perturbed in cortical malformations.Cell biological regulation of division fate in vertebrate neuroepithelial cells.iASPP, a previously unidentified regulator of desmosomes, prevents arrhythmogenic right ventricular cardiomyopathy (ARVC)-induced sudden death.The role of Rho GTPase proteins in CNS neuronal migration.ASPP2 links the apical lateral polarity complex to the regulation of YAP activity in epithelial cells.Reduced ventricular proliferation in the foetal cortex following maternal inflammation in the mouse.Autophagic activity dictates the cellular response to oncogenic RAS.Nuclear iASPP may facilitate prostate cancer progression.N terminus of ASPP2 binds to Ras and enhances Ras/Raf/MEK/ERK activation to promote oncogene-induced senescenceASPP1/2-PP1 complexes are required for chromosome segregation and kinetochore-microtubule attachments.New spin on an old transition: epithelial parallels in neuronal adhesion control.The N and C termini of ZO-1 are surrounded by distinct proteins and functional protein networks.Small Interfering RNA Targeted to ASPP2 Promotes Progression of Experimental Proliferative Vitreoretinopathy.Formation of chimeric genes by copy-number variation as a mutational mechanism in schizophrenia.ASPP2 involvement in p53-mediated HIV-1 envelope glycoprotein gp120 neurotoxicity in mice cerebrocortical neurons.Upregulation of MiR-205 under hypoxia promotes epithelial-mesenchymal transition by targeting ASPP2.Evolution of cerebral cortical development.Progenitor genealogy in the developing cerebral cortex.Loss of MAP3K1 enhances proliferation and apoptosis during retinal development.Adherens Junction and E-Cadherin complex regulation by epithelial polarity.ASPP1 and ASPP2 bind active RAS, potentiate RAS signalling and enhance p53 activity in cancer cells.An indirect role for ASPP1 in limiting p53-dependent p21 expression and cellular senescence.Cytoplasmic ASPP1 inhibits apoptosis through the control of YAP.Restoration of MAGI-1 expression in human papillomavirus-positive tumor cells induces cell growth arrest and apoptosis.
P2860
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P2860
ASPP2 binds Par-3 and controls the polarity and proliferation of neural progenitors during CNS development.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
ASPP2 binds Par-3 and controls ...... nitors during CNS development.
@en
type
label
ASPP2 binds Par-3 and controls ...... nitors during CNS development.
@en
prefLabel
ASPP2 binds Par-3 and controls ...... nitors during CNS development.
@en
P2093
P50
P1433
P1476
ASPP2 binds Par-3 and controls ...... nitors during CNS development.
@en
P2093
Amanda Cheung
Carles Gaston-Massuet
Indrika Ratnayaka
Luca Tordella
Mark Shipman
Roberta Sottocornola
Shan Zhong
Virginie Vives
P304
P356
10.1016/J.DEVCEL.2010.06.003
P407
P577
2010-07-08T00:00:00Z