WISP3-dependent regulation of type II collagen and aggrecan production in chondrocytes.
about
WISP3, the gene responsible for the human skeletal disease progressive pseudorheumatoid dysplasia, is not essential for skeletal function in miceNormal growth and development in mice over-expressing the CCN family member WISP3Inhibition of CCN6 (WISP3) expression promotes neoplastic progression and enhances the effects of insulin-like growth factor-1 on breast epithelial cells.Cooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilageMustn1 is expressed during chondrogenesis and is necessary for chondrocyte proliferation and differentiation in vitroCYR61/CCN1 and WISP3/CCN6 are chemoattractive ligands for human multipotent mesenchymal stroma cells.Oxidative stress inhibits insulin-like growth factor-I induction of chondrocyte proteoglycan synthesis through differential regulation of phosphatidylinositol 3-Kinase-Akt and MEK-ERK MAPK signaling pathways.Transcriptional coactivator PGC-1alpha regulates chondrogenesis via association with Sox9The CCN proteins: important signaling mediators in stem cell differentiation and tumorigenesis.The CCN family member Wisp3, mutant in progressive pseudorheumatoid dysplasia, modulates BMP and Wnt signalingDual regulation of metalloproteinase expression in chondrocytes by Wnt-1-inducible signaling pathway protein 3/CCN6.Novel COL2A1 variant (c.619G>A, p.Gly207Arg) manifesting as a phenotype similar to progressive pseudorheumatoid dysplasia and spondyloepiphyseal dysplasia, Stanescu typeWISP3 mutational analysis in Indian patients diagnosed with progressive pseudorheumatoid dysplasia and report of a novel mutation at p.Y198.Cartilage cell clusters.The diagnostic challenge of progressive pseudorheumatoid dysplasia (PPRD): a review of clinical features, radiographic features, and WISP3 mutations in 63 affected individuals.Genomic structure and functional characterization of the promoter region of human IkappaB kinase-related kinase IKKi/IKKvarepsilon gene.Articular cartilage: from formation to tissue engineering.A homozygous deletion of exon 1 in WISP3 causes progressive pseudorheumatoid dysplasia in two siblings.Multiple enhancers associated with ACAN suggest highly redundant transcriptional regulation in cartilage.Three Cases of Spondyloepiphyseal Dysplasia Tarda in One Korean Family.Expression of WISP3 and RhoC genes at mRNA and protein levels in inflammatory and noninflammatory breast cancer in Tunisian patients.Delayed-onset of progressive pseudorheumatoid dysplasia in a Chinese adult with a novel compound WISP3 mutation: a case report.Late diagnosis of a truncating WISP3 mutation results in a severe phenotype of progressive pseudorheumatoid dysplasia.Expression of CCN Genes and Proteins in Human Skin: Methods and Protocols.Novel and recurrent mutations in WISP3 and an atypical phenotype.Progressive pseudorheumatoid dysplasia with new-found gene mutation of Wntl inducible signaling pathway protein 3
P2860
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P2860
WISP3-dependent regulation of type II collagen and aggrecan production in chondrocytes.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
WISP3-dependent regulation of type II collagen and aggrecan production in chondrocytes.
@en
type
label
WISP3-dependent regulation of type II collagen and aggrecan production in chondrocytes.
@en
prefLabel
WISP3-dependent regulation of type II collagen and aggrecan production in chondrocytes.
@en
P2093
P356
P1476
WISP3-dependent regulation of type II collagen and aggrecan production in chondrocytes.
@en
P2093
Dennis A Carson
Malini Sen
Martin K Lotz
Mary B Goldring
Yu-Ho Cheng
P304
P356
10.1002/ART.20005
P577
2004-02-01T00:00:00Z