Characterization of new oral antidiabetic agent CS-045. Studies in KK and ob/ob mice and Zucker fatty rats.
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Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivationEffects of a water-soluble extract of maitake mushroom on circulating glucose/insulin concentrations in KK miceFibrates, glitazones, and peroxisome proliferator-activated receptorsEffect of troglitazone on plasma lipid metabolism and lipoprotein lipaseChronic and acute effects of thiazolidinediones BM13.1258 and BM15.2054 on rat skeletal muscle glucose metabolismLeptin, troglitazone, and the expression of sterol regulatory element binding proteins in liver and pancreatic isletsLeptin- or troglitazone-induced lipopenia protects islets from interleukin 1beta cytotoxicityTroglitazone inhibits vascular smooth muscle cell growth and intimal hyperplasiaTroglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker ratsLipid lowering explains the insulin sensitivity enhancing effects of a thiazolidinedione, 5-(4-(2-(2-phenyl-4-oxazolyl)ethoxy)benzyl)-2,4 thiazolidinedione.The emerging role of thiazolidinediones in the treatment of diabetes-mellitus and related disorders.Thiazolidinediones--the new insulin enhancers.Thiazolidinediones: a new class of antidiabetic drugs.NR4A orphan nuclear receptors: transcriptional regulators of gene expression in metabolism and vascular biology.Treatment of insulin resistance with peroxisome proliferator-activated receptor gamma agonistsInsulin sensitiser drugs.Emerging therapeutic opportunities for skeletal restoration.Development of Therapeutics That Induce Mitochondrial Biogenesis for the Treatment of Acute and Chronic Degenerative Diseases.Differentiating members of the thiazolidinedione class: a focus on efficacy.Xenobiotic metabolism, disposition, and regulation by receptors: from biochemical phenomenon to predictors of major toxicitiesEffects of free fatty acids on insulin secretion in obesity.Rosiglitazone ameliorates abnormal expression and activity of protein tyrosine phosphatase 1B in the skeletal muscle of fat-fed, streptozotocin-treated diabetic rats.PPARγ: a circadian transcription factor in adipogenesis and osteogenesis.Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discoveryClinical review: adiponectin biology and its role in inflammation and critical illness.Promyelocytic leukemia inhibits adipogenesis, and loss of promyelocytic leukemia results in fat accumulation in mice.Troglitazone prevents mitochondrial alterations, beta cell destruction, and diabetes in obese prediabetic rats.The orphan nuclear receptor small heterodimer partner is required for thiazolidinedione effects in leptin-deficient mice.Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes.Can the electrophysiological action of rosiglitazone explain its cardiac side effects?Drug bioactivation, covalent binding to target proteins and toxicity relevance.Sargassum coreanum extract alleviates hyperglycemia and improves insulin resistance in db/db diabetic miceRole of peroxisome proliferator-activated receptor alpha in disease of pancreatic beta cells.The Development of INT131 as a Selective PPARgamma Modulator: Approach to a Safer Insulin SensitizerImproved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiency.Gynura procumbens extract improves insulin sensitivity and suppresses hepatic gluconeogenesis in C57BL/KsJ-db/db mice.Treatment with the oral antidiabetic agent troglitazone improves beta cell responses to glucose in subjects with impaired glucose tolerance.Troglitazone, but not rosiglitazone, damages mitochondrial DNA and induces mitochondrial dysfunction and cell death in human hepatocytes.PPAR-γ Agonists As Antineoplastic Agents in Cancers with Dysregulated IGF Axis.Thiazolidine derivatives ameliorate high glucose-induced insulin resistance via the normalization of protein-tyrosine phosphatase activities.
P2860
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P2860
Characterization of new oral antidiabetic agent CS-045. Studies in KK and ob/ob mice and Zucker fatty rats.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Characterization of new oral a ...... ob mice and Zucker fatty rats.
@en
type
label
Characterization of new oral a ...... ob mice and Zucker fatty rats.
@en
prefLabel
Characterization of new oral a ...... ob mice and Zucker fatty rats.
@en
P2093
P356
P1433
P1476
Characterization of new oral a ...... ob mice and Zucker fatty rats.
@en
P2093
Fujiwara T
Horikoshi H
Ushiyama I
Yoshioka S
Yoshioka T
P304
P356
10.2337/DIAB.37.11.1549
P407
P577
1988-11-01T00:00:00Z