A rearrangement of the guanosine-binding site establishes an extended network of functional interactions in the Tetrahymena group I ribozyme active site.
about
Comparison of a PreQ1 Riboswitch Aptamer in Metabolite-bound and Free States with Implications for Gene Regulation2'-Fluoro substituents can mimic native 2'-hydroxyls within structured RNA.Structure-function analysis from the outside in: long-range tertiary contacts in RNA exhibit distinct catalytic roles.An active site rearrangement within the Tetrahymena group I ribozyme releases nonproductive interactions and allows formation of catalytic interactions.Determination of hepatitis delta virus ribozyme N(-1) nucleobase and functional group specificity using internal competition kineticsTesting the nearest neighbor model for canonical RNA base pairs: revision of GU parameters.Tightening of active site interactions en route to the transition state revealed by single-atom substitution in the guanosine-binding site of the Tetrahymena group I ribozyme.Quantitative tests of a reconstitution model for RNA folding thermodynamics and kinetics.Phosphodiester models for cleavage of nucleic acids.Understanding catalysis of phosphate-transfer reactions by the large ribozymes.
P2860
Q27667887-235D373F-9BA6-4D80-80B8-D49EFF21A995Q35197859-3DF28B76-001D-4780-B227-5C6ACA960494Q35269518-0DDE6197-74AB-4F0D-AAD0-802671AB6E1BQ36406303-4FA9B991-F128-4916-AF0E-E6D8B1720F74Q40982107-1F3221A4-E3C8-4D13-B9D5-392E33636189Q42133423-58519498-AFB3-4563-9C38-215AB7EA38D6Q42224763-7B0E392F-22AB-42CE-95BE-02BE2E3FB2DEQ47756940-4E03618A-6C56-4CAC-9A42-10637E5A7D75Q52714621-46FA807A-96DE-4887-AA32-DABC818278CBQ54361107-E171E67F-710E-419C-B360-F69E09BF563D
P2860
A rearrangement of the guanosine-binding site establishes an extended network of functional interactions in the Tetrahymena group I ribozyme active site.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
A rearrangement of the guanosi ...... group I ribozyme active site.
@en
type
label
A rearrangement of the guanosi ...... group I ribozyme active site.
@en
prefLabel
A rearrangement of the guanosi ...... group I ribozyme active site.
@en
P2093
P2860
P356
P1433
P1476
A rearrangement of the guanosi ...... a group I ribozyme active site
@en
P2093
Daniel Herschlag
Joseph A Piccirilli
Raghuvir N Sengupta
P2860
P304
P356
10.1021/BI902200N
P407
P577
2010-03-01T00:00:00Z