Suppression of breast cancer by chemical modulation of vulnerable zinc fingers in estrogen receptor.
about
Redox-directed cancer therapeutics: molecular mechanisms and opportunitiesPaving the Road to Tumor Development and Spreading: Myeloid-Derived Suppressor Cells are Ruling the FateDevelopment of new estrogen receptor-targeting therapeutic agents for tamoxifen-resistant breast cancerLigand-dependent activation of the farnesoid X-receptor directs arginine methylation of histone H3 by CARM1Reactivity of zinc finger cysteines: chemical modifications within labile zinc fingers in estrogen receptor.In search of novel drug target sites on estrogen receptors using RNA aptamers.Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer.A cooperative and specific DNA-binding mode of HIV-1 integrase depends on the nature of the metallic cofactor and involves the zinc-containing N-terminal domain.Genome-wide analysis of estrogen receptor alpha DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation.Selectively targeting estrogen receptors for cancer treatment.Small molecule inhibitors as probes for estrogen and androgen receptor actionPotential mechanisms of estrogen quinone carcinogenesis.Enhancement of the physicochemical properties of [Pt(dien)(nucleobase)]2+ for HIVNCp7 targeting.A Role for PPARgamma in the Regulation of Cytokines in Immune Cells and Cancer.A new small molecule inhibitor of estrogen receptor alpha binding to estrogen response elements blocks estrogen-dependent growth of cancer cells.Designer monotransregulators provide a basis for a transcriptional therapy for de novo endocrine-resistant breast cancer.Zinc finger proteins as templates for metal ion exchange and ligand reactivity. Chemical and biological consequences.Beyond the ligand-binding pocket: targeting alternate sites in nuclear receptors.Modulation of nuclear receptor function by cellular redox poise.Genomic responses from the estrogen-responsive element-dependent signaling pathway mediated by estrogen receptor alpha are required to elicit cellular alterations.Zinc Finger-Containing Cellular Transcription Corepressor ZBTB25 Promotes Influenza Virus RNA Transcription and Is a Target for Zinc Ejector Drugs.Au(iii) compounds as HIV nucleocapsid protein (NCp7)-nucleic acid antagonists.QSAR-assisted virtual screening of lead-like molecules from marine and microbial natural sources for antitumor and antibiotic drug discovery.Molecular mechanism of estrogen-estrogen receptor signaling.
P2860
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P2860
Suppression of breast cancer by chemical modulation of vulnerable zinc fingers in estrogen receptor.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Suppression of breast cancer b ...... fingers in estrogen receptor.
@en
type
label
Suppression of breast cancer b ...... fingers in estrogen receptor.
@en
prefLabel
Suppression of breast cancer b ...... fingers in estrogen receptor.
@en
P2093
P356
P1433
P1476
Suppression of breast cancer b ...... fingers in estrogen receptor.
@en
P2093
Andrew T Maynard
Ettore Appella
Kelly Mihalic
Li Hua Wang
Weihua Xiao
William L Farrar
Xiao Yi Yang
Xiaohu Zhang
Ying-Xin Fan
P2888
P356
10.1038/NM969
P407
P50
P577
2003-12-14T00:00:00Z