Amelioration of glucose intolerance by the synthetic androstene HE3286: link to inflammatory pathways.
about
Molecular targets for 17α-ethynyl-5-androstene-3β,7β,17β-triol, an anti-inflammatory agent derived from the human metabolome5-Androstene-3β,7β,17β-triol (β-AET) slows thermal injury induced osteopenia in mice: relation to aging and osteoporosis17α-alkynyl 3α, 17β-androstanediol non-clinical and clinical pharmacology, pharmacokinetics and metabolism.A new antidiabetic compound attenuates inflammation and insulin resistance in Zucker diabetic fatty rats.HE3286 reduces axonal loss and preserves retinal ganglion cell function in experimental optic neuritis.HE3286, an oral synthetic steroid, treats lung inflammation in mice without immune suppression.Studies of the pharmacology of 17α-ethynyl-androst-5-ene-3β,7β,17β-triol, a synthetic anti-inflammatory androstene.Monocyte Chemoattractant Protein 1 (MCP-1) in obesity and diabetesPeriodontitis and insulin resistance: casual or causal relationship?An anti-inflammatory sterol decreases obesity-related inflammation-induced insulin resistance and metabolic dysregulation.Oral Delivery of a Synthetic Sterol Reduces Axonopathy and Inflammation in a Rodent Model of Glaucoma.Phase I and Phase II clinical trials of androst-5-ene-3β,7β,17β-triol.A synthetic anti-inflammatory sterol improves insulin sensitivity in insulin-resistant obese impaired glucose tolerance subjects.A potential role for 5-androstene-3β,7β,17β-triol in obesity and metabolic syndrome.
P2860
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P2860
Amelioration of glucose intolerance by the synthetic androstene HE3286: link to inflammatory pathways.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Amelioration of glucose intole ...... link to inflammatory pathways.
@en
type
label
Amelioration of glucose intole ...... link to inflammatory pathways.
@en
prefLabel
Amelioration of glucose intole ...... link to inflammatory pathways.
@en
P2093
P356
P1476
Amelioration of glucose intole ...... link to inflammatory pathways.
@en
P2093
Chris Reading
Clarence Ahlem
David Alleva
Jaime Flores-Riveros
James M Frincke
Sonia Villegas
Steve K White
Tianlun Wang
Yujin Huang
P356
10.1124/JPET.109.161182
P407
P577
2010-01-12T00:00:00Z