Pioglitazone preserves pancreatic islet structure and insulin secretory function in three murine models of type 2 diabetes.
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Pioglitazone acutely reduces insulin secretion and causes metabolic deceleration of the pancreatic beta-cell at submaximal glucose concentrationsTranscriptional regulation of lipid metabolism by fatty acids: a key determinant of pancreatic beta-cell functionPancreatic regulation of glucose homeostasisCurrent status and patent prospective of animal models in diabetic researchAn intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic beta cells.Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure.Molecular mechanism by which pioglitazone preserves pancreatic beta-cells in obese diabetic mice: evidence for acute and chronic actions as a PPARgamma agonist.Pharmacogenetics of Anti-Diabetes Drugs.Enhancing pancreatic Beta-cell regeneration in vivo with pioglitazone and alogliptin.Pioglitazone and sulfonylureas: effectively treating type 2 diabetesInvestigational agents that protect pancreatic islet beta-cells from failure.Update on the protective molecular pathways improving pancreatic beta-cell dysfunctionInhibition of human insulin gene transcription by peroxisome proliferator-activated receptor gamma and thiazolidinedione oral antidiabetic drugsBeta-cell protection and therapy for latent autoimmune diabetes in adults.Latent autoimmune diabetes in the adults (LADA) in Asia: from pathogenesis and epidemiology to therapy.Do thiazolidinediones still have a role in treatment of type 2 diabetes mellitus?The ongoing pursuit of neuroprotective therapies in Parkinson disease.Structural and functional analysis of pancreatic islets preserved by pioglitazone in db/db mice.Which is the eligible patient to be treated with pioglitazone? The expert view.ERp46 is reduced by high glucose and regulates insulin content in pancreatic beta-cells.Quantitative histopathological assessment of retardation of islets of langerhans degeneration in rosiglitazone-dosed obese ZDF rats using combined insulin and collagens (I and III) immunohistochemistry with automated image analysis and statistical mComparison of the antidiabetic effects of brain-derived neurotrophic factor and thiazolidinediones in obese diabetic mice.Practical strategies for improving outcomes in T2DM: The potential role of pioglitazone and DPP4 inhibitors.Liraglutide, a human glucagon-like peptide-1 analogue, stimulates AKT-dependent survival signalling and inhibits pancreatic β-cell apoptosis.Effect of initial combination therapy with sitagliptin, a dipeptidyl peptidase-4 inhibitor, and pioglitazone on glycemic control and measures of β-cell function in patients with type 2 diabetes.Thiazolidinediones improve beta-cell function in type 2 diabetic patients.Angiotensin II receptor blocker provides pancreatic beta-cell protection independent of blood pressure lowering in diabetic db/db mice.Pioglitazone attenuates fatty acid-induced oxidative stress and apoptosis in pancreatic beta-cells.
P2860
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P2860
Pioglitazone preserves pancreatic islet structure and insulin secretory function in three murine models of type 2 diabetes.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Pioglitazone preserves pancrea ...... ine models of type 2 diabetes.
@en
type
label
Pioglitazone preserves pancrea ...... ine models of type 2 diabetes.
@en
prefLabel
Pioglitazone preserves pancrea ...... ine models of type 2 diabetes.
@en
P2093
P2860
P1476
Pioglitazone preserves pancrea ...... ine models of type 2 diabetes.
@en
P2093
Beatrice Wyse
F T Murray
Geri Sawada
Mehmood Khan
P2860
P304
P356
10.1152/AJPENDO.00331.2003
P577
2003-10-07T00:00:00Z