The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation. - Wikidata - wikimedia - TriplyDB

The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation.

The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation.

http://www.wikidata.org/entity/Q38352705

about

An immunogenic peptide in the A-box of HMGB1 protein reverses apoptosis-induced tolerance through RAGE receptor High mobility group box protein 1 (HMGB1)-partner molecule complexes enhance cytokine production by signaling through the partner molecule receptor NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy?Emerging role of HMGB1 in fibrotic diseases Mucins and toll-like receptors: kith and kin in infection and cancer Cell death in the pathogenesis of immune-mediated diseases: the role of HMGB1 and DAMP-PAMP complexes Targeting inflammation as a therapeutic strategy for drug-resistant epilepsies: an update of new immune-modulating approaches The translocation of nuclear molecules during inflammation and cell death Microparticles as mediators and biomarkers of rheumatic disease Extracellular high-mobility group box 1 protein (HMGB1) as a mediator of persistent pain Vitreous mediators in retinal hypoxic diseases Extracellular administration of BCL2 protein reduces apoptosis and improves survival in a murine model of sepsis Extracellular BCL2 proteins are danger-associated molecular patterns that reduce tissue damage in murine models of ischemia-reperfusion injury Extracellular HMGB1 regulates multi-walled carbon nanotube-induced inflammation in vivo The IKKα-dependent NF-κB p52/RelB noncanonical pathway is essential to sustain a CXCL12 autocrine loop in cells migrating in response to HMGB1.Cell migration to CXCL12 requires simultaneous IKKα and IKKβ-dependent NF-κB signaling Toll-like receptor signaling and stages of addiction.The HMGB1-RAGE axis mediates traumatic brain injury-induced pulmonary dysfunction in lung transplantation.The danger signal S100B integrates pathogen- and danger-sensing pathways to restrain inflammation Chondrocyte innate immune myeloid differentiation factor 88-dependent signaling drives procatabolic effects of the endogenous Toll-like receptor 2/Toll-like receptor 4 ligands low molecular weight hyaluronan and high mobility group box chromosomal p Inhibitor of NF-kappa B kinases alpha and beta are both essential for high mobility group box 1-mediated chemotaxis [corrected]The oxidative stress product carboxyethylpyrrole potentiates TLR2/TLR1 inflammatory signaling in macrophages High mobility group box 1 potentiates the pro-inflammatory effects of interleukin-1β in osteoarthritic synoviocytes.High-mobility group box 1 represents a potential marker of disease activity and novel therapeutic target in systemic lupus erythematosus.Prevalence and clinical significance of sterile intra-amniotic inflammation in patients with preterm labor and intact membranes Sputum biomarkers and the prediction of clinical outcomes in patients with cystic fibrosis.HMGB1 in health and disease.Galectin-3 functions as an alarmin: pathogenic role for sepsis development in murine respiratory tularemia.TLR4-dependent activation of dendritic cells by an HMGB1-derived peptide adjuvant.The C-terminal acidic tail is responsible for the inhibitory effects of HMGB1 on efferocytosis.Dipotassium Glycyrrhizate Inhibits HMGB1-Dependent Inflammation and Ameliorates Colitis in Mice Mechanical ventilation enhances HMGB1 expression in an LPS-induced lung injury model.Immune dysregulation by the rheumatoid arthritis shared epitope.Red blood cells induce necroptosis of lung endothelial cells and increase susceptibility to lung inflammation.The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis.Anti-HMGB1 monoclonal antibody ameliorates immunosuppression after peripheral tissue trauma: attenuated T-lymphocyte response and increased splenic CD11b (+) Gr-1 (+) myeloid-derived suppressor cells require HMGB1.TLR9 and the NLRP3 inflammasome link acinar cell death with inflammation in acute pancreatitis.High mobility group protein B1 (HMGB1) in Asthma: comparison of patients with chronic obstructive pulmonary disease and healthy controls.High systemic levels of the cytokine-inducing HMGB1 isoform secreted in severe macrophage activation syndrome.HMGB1 and microparticles as mediators of the immune response to cell death.

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P2860

The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation.

http://www.wikidata.org/entity/Q38352705

description

2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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2009年學術文章

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2009年學術文章

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name

The alarmin HMGB1 acts in syne ...... gnals to promote inflammation.

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The alarmin HMGB1 acts in syne ...... gnals to promote inflammation.

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The alarmin HMGB1 acts in syne ...... gnals to promote inflammation.

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P1433

Journal of Leukocyte Biology

P1476

The alarmin HMGB1 acts in syne ...... ignals to promote inflammation

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P2093

Ann-Charlotte Aveberger

http://www.w3.org/2001/XMLSchema#string

Hanna Schierbeck

http://www.w3.org/2001/XMLSchema#string

Heidi Wähämaa

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Helena Erlandsson Harris

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Hulda Sigridur Hreggvidsdottir

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Lars Ottosson

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Lena Klevenvall

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Therese Ostberg

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P2860

HMGB1: endogenous danger signaling

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

HMG-1 as a late mediator of endotoxin lethality in mice

High mobility group box 1 protein interacts with multiple Toll-like receptors

Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation

High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes

Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE

Regulation of DNA-dependent activities by the functional motifs of the high-mobility-group chromosomal proteins.

Anti-HMGB1 neutralizing antibody ameliorates gut barrier dysfunction and improves survival after hemorrhagic shock

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655-662

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10.1189/JLB.0908548

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3

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86

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26328590

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19564572

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