NMR chemical exchange as a probe for ligand-binding kinetics in a theophylline-binding RNA aptamer.
about
Structural determinants for ligand capture by a class II preQ 1 riboswitchMolecular basis for the wide range of affinity found in Csr/Rsm protein-RNA recognitionChemical exchange in biomacromolecules: past, present, and future.From induced fit to conformational selection: a continuum of binding mechanism controlled by the timescale of conformational transitionsCharacterizing RNA dynamics at atomic resolution using solution-state NMR spectroscopySELEX Modifications and Bioanalytical Techniques for Aptamer-Target Binding Characterization.Molecular simulations and Markov state modeling reveal the structural diversity and dynamics of a theophylline-binding RNA aptamer in its unbound stateRegulatory interactions between a bacterial tyrosine kinase and its cognate phosphatase.Optimization of Experimental Parameters to Explore Small-Ligand/Aptamer Interactions through Use of (1) H NMR Spectroscopy and Molecular Modeling.RNA aptamers as genetic control devices: the potential of riboswitches as synthetic elements for regulating gene expression.Conformational dynamics of the tetracycline-binding aptamer.Ligand-induced conformational capture of a synthetic tetracycline riboswitch revealed by pulse EPR.Ultrafast dynamics show that the theophylline and 3-methylxanthine aptamers employ a conformational capture mechanism for binding their ligands.Reagentless, Structure-Switching, Electrochemical Aptamer-Based Sensors.Protein dynamics and function from solution state NMR spectroscopy.(S)Pinning down protein interactions by NMR.Discovery of selective bioactive small molecules by targeting an RNA dynamic ensemble.Tractable RNA-ligand interaction kinetics.Slow molecular recognition by RNA.An invisible ubiquitin conformation is required for efficient phosphorylation by PINK1.Polyoxometalates as sialidase mimics: selective and non-destructive removal of sialic acid from a glycoprotein promoted by phosphotungstic acid.Aptamer-affinity column clean-up coupled with ultra high performance liquid chromatography and fluorescence detection for the rapid determination of ochratoxin A in ginger powder.
P2860
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P2860
NMR chemical exchange as a probe for ligand-binding kinetics in a theophylline-binding RNA aptamer.
description
2009 nî lūn-bûn
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2009年の論文
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
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@zh-sg
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name
NMR chemical exchange as a pro ...... ophylline-binding RNA aptamer.
@en
type
label
NMR chemical exchange as a pro ...... ophylline-binding RNA aptamer.
@en
prefLabel
NMR chemical exchange as a pro ...... ophylline-binding RNA aptamer.
@en
P2860
P356
P1476
NMR chemical exchange as a pro ...... eophylline-binding RNA aptamer
@en
P2093
Arthur Pardi
Grant R Zimmermann
P2860
P304
P356
10.1021/JA900695M
P407
P577
2009-04-01T00:00:00Z