Functional analysis of a p21WAF1,CIP1,SDI1 mutant (Arg94 --> Trp) identified in a human breast carcinoma. Evidence that the mutation impairs the ability of p21 to inhibit cyclin-dependent kinases.
about
Effects of histone acetylation and DNA methylation on p21( WAF1) regulationGenomic imbalance in rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridinep21 in cancer: intricate networks and multiple activitiesHuman papillomavirus E7 oncoprotein overrides the tumor suppressor activity of p21Cip1 in cervical carcinogenesis.Induction of p21(WAF1/CIP1) and inhibition of Cdk2 mediated by the tumor suppressor p16(INK4a)P27 in cell cycle control and cancer.Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein.The p21Waf1 pathway is involved in blocking leukemogenesis by the t(8;21) fusion protein AML1-ETO.Nucleolar GTP-binding Protein-1 (NGP-1) Promotes G1 to S Phase Transition by Activating Cyclin-dependent Kinase Inhibitor p21 Cip1/Waf1.Tamoxifen-stimulated growth of breast cancer due to p21 lossP21 and p27: roles in carcinogenesis and drug resistance.The p21(WAF1/CIP1) promoter is methylated in Rat-1 cells: stable restoration of p53-dependent p21(WAF1/CIP1) expression after transfection of a genomic clone containing the p21(WAF1/CIP1) gene.Linkage analysis of familial melanoma and chromosome 6 in 14 Australian kindreds.p21WAF1/Cip1 is associated with cyclin D1CCND1 expression and tubular differentiation but is independent of p53 overexpression in human breast carcinoma.The KIP/CIP family members p21^{Waf1/Cip1} and p57^{Kip2} as diagnostic markers for breast cancer.
P2860
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P2860
Functional analysis of a p21WAF1,CIP1,SDI1 mutant (Arg94 --> Trp) identified in a human breast carcinoma. Evidence that the mutation impairs the ability of p21 to inhibit cyclin-dependent kinases.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Functional analysis of a p21WA ...... ibit cyclin-dependent kinases.
@en
type
label
Functional analysis of a p21WA ...... ibit cyclin-dependent kinases.
@en
prefLabel
Functional analysis of a p21WA ...... ibit cyclin-dependent kinases.
@en
P2093
P2860
P356
P1476
Functional analysis of a p21WA ...... hibit cyclin-dependent kinases
@en
P2093
P2860
P304
15782-15786
P356
10.1074/JBC.271.26.15782
P407
P577
1996-06-01T00:00:00Z