The yin-yang of kinase activation and unfolding explains the peculiarity of Val600 in the activation segment of BRAF.
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Predicting the impact of Lynch syndrome-causing missense mutations from structural calculationsEnsemble-based modeling and rigidity decomposition of allosteric interaction networks and communication pathways in cyclin-dependent kinases: Differentiating kinase clients of the Hsp90-Cdc37 chaperone.Atomistic simulations and network-based modeling of the Hsp90-Cdc37 chaperone binding with Cdk4 client protein: A mechanism of chaperoning kinase clients by exploiting weak spots of intrinsically dynamic kinase domains.Natural (and Unnatural) Small Molecules as Pharmacological Chaperones and Inhibitors in Cancer.Network-based modelling and percolation analysis of conformational dynamics and activation in the CDK2 and CDK4 proteins: dynamic and energetic polarization of the kinase lobes may determine divergence of the regulatory mechanisms.Evolutionary Divergent Suppressor Mutations in Conformational DiseasesHierarchical Organization Endows the Kinase Domain with Regulatory Plasticity
P2860
Q36350781-4C89BED7-FF7F-45C2-B626-F7A4A4B8F6C2Q45335193-2D12AA94-D6E8-4ADF-BE01-3B477DB90F34Q47265199-055E6CB2-18BC-4B9E-953B-C2F54AA53774Q47673940-A1B08341-C382-47E4-A290-FBF073A8FCBAQ47779695-A00438CC-BD8C-4760-AA96-AF2503A2A288Q57578354-84EA16E0-10CA-4985-BC52-6135EEB6C56BQ57790630-C7B87648-521D-4120-8ADF-E9AB4EE0D2CA
P2860
The yin-yang of kinase activation and unfolding explains the peculiarity of Val600 in the activation segment of BRAF.
description
2016 nî lūn-bûn
@nan
2016年の論文
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2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
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2016年學術文章
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name
The yin-yang of kinase activat ...... he activation segment of BRAF.
@en
type
label
The yin-yang of kinase activat ...... he activation segment of BRAF.
@en
prefLabel
The yin-yang of kinase activat ...... he activation segment of BRAF.
@en
P2860
P356
P1433
P1476
The yin-yang of kinase activat ...... he activation segment of BRAF.
@en
P2093
Christina Kiel
Luis Serrano
P2860
P304
P356
10.7554/ELIFE.12814
P407
P577
2016-01-08T00:00:00Z