Effects of mutations of ABCA1 in the first extracellular domain on subcellular trafficking and ATP binding/hydrolysis.
about
Human ABCA7 supports apolipoprotein-mediated release of cellular cholesterol and phospholipid to generate high density lipoproteinAdrenoleukodystrophy: subcellular localization and degradation of adrenoleukodystrophy protein (ALDP/ABCD1) with naturally occurring missense mutationsDifferential phospholipid substrates and directional transport by ATP-binding cassette proteins ABCA1, ABCA7, and ABCA4 and disease-causing mutantsMammalian P4-ATPases and ABC transporters and their role in phospholipid transportThe interaction of ApoA-I and ABCA1 triggers signal transduction pathways to mediate efflux of cellular lipidsPhosphorylation of a pest sequence in ABCA1 promotes calpain degradation and is reversed by ApoA-IUnexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer.Alpha1-syntrophin modulates turnover of ABCA1.Prediction of disease-related mutations affecting protein localization.ABCA1, ABCG1, and ABCG4 are distributed to distinct membrane meso-domains and disturb detergent-resistant domains on the plasma membrane.HIV-1 protein Nef inhibits activity of ATP-binding cassette transporter A1 by targeting endoplasmic reticulum chaperone calnexinFunctional and trafficking defects in ATP binding cassette A3 mutants associated with respiratory distress syndrome.Characterization and classification of ATP-binding cassette transporter ABCA3 mutants in fatal surfactant deficiency.ABCA3-mediated choline-phospholipids uptake into intracellular vesicles in A549 cells.ABCA1 and nascent HDL biogenesisThe reverse cholesterol transport system as a potential mediator of luteolysis in the primate corpus luteumA-Subclass ATP-Binding Cassette Proteins in Brain Lipid Homeostasis and Neurodegeneration.ABCG1 and ABCG4 Suppress γ-Secretase Activity and Amyloid β Production.Host HDL biogenesis machinery is recruited to the inclusion of Chlamydia trachomatis-infected cells and regulates chlamydial growthABCA7, a molecule with unknown function.Mechanisms for cellular cholesterol transport: defects and human disease.Protein kinase C controls vesicular transport and secretion of apolipoprotein E from primary human macrophages.Both STAT3 activation and cholesterol efflux contribute to the anti-inflammatory effect of apoA-I/ABCA1 interaction in macrophages.ABCA1 mutants reveal an interdependency between lipid export function, apoA-I binding activity, and Janus kinase 2 activation.Sphingomyelin depletion impairs anionic phospholipid inward translocation and induces cholesterol efflux.Genetic variation in ABC transporter A1 contributes to HDL cholesterol in the general population.Lipid outward translocation by ABC proteins.ATP-binding cassette proteins involved in glucose and lipid homeostasis.ABC proteins protect the human body and maintain optimal health.Function and regulation of ABCA1--membrane meso-domain organization and reorganization.Oxysterols trigger ABCA1-mediated basolateral surfactant efflux.Genetic and/or non-genetic causes for inter-individual and inter-cellular variability in transporter protein expression: implications for understanding drug efficacy and toxicity.Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol.Liver X receptor beta (LXRbeta) interacts directly with ATP-binding cassette A1 (ABCA1) to promote high density lipoprotein formation during acute cholesterol accumulation.Sodium taurocholate-dependent lipid efflux by ABCA1: effects of W590S mutation on lipid translocation and apolipoprotein A-I dissociation.ATP hydrolysis-dependent conformational changes in the extracellular domain of ABCA1 are associated with apoA-I bindingDirect interaction of nuclear liver X receptor-beta with ABCA1 modulates cholesterol efflux.Sphingomyelin-dependence of cholesterol efflux mediated by ABCG1.Enhanced apoA-I-dependent cholesterol efflux by ABCA1 from sphingomyelin-deficient Chinese hamster ovary cells.Purification and ATPase activity of human ABCA1.
P2860
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P2860
Effects of mutations of ABCA1 in the first extracellular domain on subcellular trafficking and ATP binding/hydrolysis.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Effects of mutations of ABCA1 ...... ng and ATP binding/hydrolysis.
@en
type
label
Effects of mutations of ABCA1 ...... ng and ATP binding/hydrolysis.
@en
prefLabel
Effects of mutations of ABCA1 ...... ng and ATP binding/hydrolysis.
@en
P2093
P2860
P356
P1476
Effects of mutations of ABCA1 ...... ng and ATP binding/hydrolysis.
@en
P2093
Arowu R Tanaka
Gaku Morinaga
Kei-ichiro Okuhira
Masayuki Murata
Michinori Matsuo
Noriyuki Kioka
Shinji Yokoyama
Sumiko Abe-Dohmae
P2860
P304
P356
10.1074/JBC.M206885200
P407
P577
2002-12-31T00:00:00Z