The quaking gene product necessary in embryogenesis and myelination combines features of RNA binding and signal transduction proteins.
about
A family of human RNA-binding proteins related to the Drosophila Bruno translational regulatorSik (BRK) phosphorylates Sam68 in the nucleus and negatively regulates its RNA binding abilityHuman Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteinsStructure-function analysis of Qk1: a lethal point mutation in mouse quaking prevents homodimerization.Function of quaking in myelination: regulation of alternative splicing.Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1Sam68 enhances the cytoplasmic utilization of intron-containing RNA and is functionally regulated by the nuclear kinase Sik/BRK.Human QKI, a potential regulator of mRNA expression of human oligodendrocyte-related genes involved in schizophreniaEleven densely clustered genes, six of them novel, in 176 kb of mouse t-complex DNADribble, the Drosophila KRR1p homologue, is involved in rRNA processingSelf-association of the single-KH-domain family members Sam68, GRP33, GLD-1, and Qk1: role of the KH domainIdentification of AUF1 (heterogeneous nuclear ribonucleoprotein D) as a component of the alpha-globin mRNA stability complexThe STAR protein QKI-6 is a translational repressorCharacterization of Sam68-like mammalian proteins SLM-1 and SLM-2: SLM-1 is a Src substrate during mitosisSam68 is absolutely required for Rev function and HIV-1 productionThe Bmdsx transgene including trimmed introns is sex-specifically spliced in tissues of the silkworm, Bombyx mori.Emerging functions of the Quaking RNA-binding proteins and link to human diseasesSAM68: Signal Transduction and RNA Metabolism in Human CancerStructure of the GLD-1 homodimerization domain: insights into STAR protein-mediated translational regulation.Structural Analysis of the Quaking Homodimerization InterfaceSolution Structure of the QUA1 Dimerization Domain of pXqua, the Xenopus Ortholog of QuakingStructure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sitesArginine methylation inhibits the binding of proline-rich ligands to Src homology 3, but not WW, domainsSpecificity and determinants of Sam68 RNA binding. Implications for the biological function of K homology domainsNuclear translocation controlled by alternatively spliced isoforms inactivates the QUAKING apoptotic inducerAn Oak Ridge legacy: the specific locus test and its role in mouse mutagenesisDefective smooth muscle development in qkI-deficient miceDeletion of the Parkin coregulated gene causes male sterility in the quaking(viable) mouse mutantRNA binding protein QKI inhibits the ischemia/reperfusion-induced apoptosis in neonatal cardiomyocytesp68 Sam is a substrate of the insulin receptor and associates with the SH2 domains of p85 PI3KThe selective RNA-binding protein quaking I (QKI) is necessary and sufficient for promoting oligodendroglia differentiationQuaking regulates Hnrnpa1 expression through its 3' UTR in oligodendrocyte precursor cellsThe QKI-6 RNA binding protein regulates actin-interacting protein-1 mRNA stability during oligodendrocyte differentiation.The quaking I-5 protein (QKI-5) has a novel nuclear localization signal and shuttles between the nucleus and the cytoplasmMultiple functions of the myelin-associated glycoprotein MAG (siglec-4a) in formation and maintenance of myelinInsights into the structural basis of RNA recognition by STAR domain proteins.The drosophila melanogaster genome: translation factors and RNA binding proteinsThe QKI-6 and QKI-7 RNA binding proteins block proliferation and promote Schwann cell myelination.Discovery of candidate disease genes in ENU-induced mouse mutants by large-scale sequencing, including a splice-site mutation in nucleoredoxin.Genome analysis: RNA recognition motif (RRM) and K homology (KH) domain RNA-binding proteins from the flowering plant Arabidopsis thaliana.
P2860
Q22254606-3B26F2E8-F0AD-464A-AD77-4FB039634FCEQ22254678-CDC51C9E-FA1F-437D-84CB-51757D875B34Q24338236-FC4EB619-0F12-4829-B48B-8DCD91949ADDQ24522616-C39F6A2B-A8EA-4309-BCE0-2BC7DDC7631DQ24535989-3FFF31C6-6062-411C-B546-9F9439D5D39BQ24540397-A2C4BBC3-5A47-4CA9-A012-6CD262626CE0Q24540541-0B2F4FA2-2FCC-44BC-9F94-7EF1DA896BFDQ24544238-CF5CC541-BB84-427C-BF54-559F492AF1FAQ24623409-25D09D76-751D-4A8F-A02F-432410D78495Q24633529-CCB3FC56-8F38-48D1-9674-C5E7C855A916Q24644556-DAD471E1-F707-4907-9992-7CF15C5526BEQ24645150-E5D951BF-42FF-47C7-AA0A-35A3FC86A456Q24653713-D8D28B11-1C87-4087-B245-7C4579DBB630Q24673734-E1DBF731-4866-4E5B-9D90-D70C1FEC688DQ24791042-E2BA2346-17A4-4546-9FCF-D4148E7D72C4Q24815091-B6C9E740-5459-4CC5-90DF-A830EAFD2FDFQ26753819-CE1A9700-8EC6-4969-97F2-E8F7EFBFA98AQ26798149-011FF8C2-F7E5-4198-865D-B82221128052Q27660197-C2E53E84-D94F-4EFD-A92C-CF91C916B20CQ27673174-9D2F2722-B4B9-46C5-AC48-67FA0B450467Q27676982-6E36F06F-470D-439E-885D-4D0EA66E3F42Q27677855-C5C319BA-A8E9-4EE5-A844-7B3908F77DFDQ28140712-B334249E-6F22-495F-A2CC-EF91D643DF76Q28252179-A7DBD0F8-01E8-4405-9919-99E260134143Q28362265-184690F7-88D6-407F-8D79-50273656F230Q28379338-3852DC5E-FC5C-4D2E-BC3B-1116C7079D2BQ28506549-ED732E16-B544-4DFB-AF28-BC2BA29A11D8Q28508054-99B3EA44-6AF8-48CA-8F79-CC5B95854E29Q28564922-4E6BA665-B5E6-4EA0-8B08-9290694CFF72Q28566032-B923ECE8-70DE-4A2E-AFC8-0AFB2E0A5060Q28566561-C408A8A2-53E9-4931-8C7A-96B12C8FD517Q28576146-D3245625-F534-48E4-8329-77C80E6E69BBQ28582272-2A7BF666-9BE2-4902-8EE9-15251889CA4FQ28585178-2AFFC030-0ADC-4D20-A1A0-7C6BC0A9331DQ28588494-EF33C748-C20D-464F-941C-AE4D0CEBC092Q30397944-A6E3EEC8-9BAF-4448-AA59-30893820CFB7Q30887453-FEB77B59-DF66-4419-A5DF-6A11262B7EE7Q33466060-80FC8367-8D16-4DD7-AF6F-A2F10AB1EBFBQ33518475-B19F8E8E-4946-4144-A9E6-262C48E3C9C3Q33559531-FA842C99-EA20-4745-B8D4-B5A2602073DD
P2860
The quaking gene product necessary in embryogenesis and myelination combines features of RNA binding and signal transduction proteins.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
The quaking gene product neces ...... signal transduction proteins.
@en
type
label
The quaking gene product neces ...... signal transduction proteins.
@en
prefLabel
The quaking gene product neces ...... signal transduction proteins.
@en
P2093
P2860
P356
P1433
P1476
The quaking gene product neces ...... signal transduction proteins.
@en
P2093
P2860
P2888
P304
P356
10.1038/NG0396-260
P407
P577
1996-03-01T00:00:00Z