Asp333, Asp495, and His523 form the catalytic triad of rat soluble epoxide hydrolase.
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The N-terminal domain of mammalian soluble epoxide hydrolase is a phosphataseLimonene-1,2-epoxide hydrolase from Rhodococcus erythropolis DCL14 belongs to a novel class of epoxide hydrolasesBacterial 2,4-dioxygenases: new members of the alpha/beta hydrolase-fold superfamily of enzymes functionally related to serine hydrolasesDetoxification of environmental mutagens and carcinogens: structure, mechanism, and evolution of liver epoxide hydrolaseBinding of alkylurea inhibitors to epoxide hydrolase implicates active site tyrosines in substrate activationRational Design of Potent and Selective Inhibitors of an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosaPurification, molecular cloning and ethylene-inducible expression of a soluble-type epoxide hydrolase from soybean (Glycine max [L.] Merr.).Cloning and expression of a novel juvenile hormone-metabolizing epoxide hydrolase during larval-pupal metamorphosis of the cabbage looper, Trichoplusia ni.Catalytic triad of microsomal epoxide hydrolase: replacement of Glu404 with Asp leads to a strongly increased turnover rate.Kinetic and chemical mechanism of epoxide hydrolase.Metabolic detoxification: implications for thresholds.New structural and chemical insight into the catalytic mechanism of epoxide hydrolases.Epoxide hydrolase activities and epoxy fatty acids in the mosquito Culex quinquefasciatus.The telltale structures of epoxide hydrolases.Angiotensin II up-regulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivoVisualizing the Mechanism of Epoxide Hydrolysis by the Bacterial Virulence Enzyme Cif.Design and discovery of soluble epoxide hydrolase inhibitors for the treatment of cardiovascular diseases.Biochemical evidence for the involvement of tyrosine in epoxide activation during the catalytic cycle of epoxide hydrolase.Identification of the ATP-binding site in the terminase subunit pUL56 of human cytomegalovirus.Soluble epoxide hydrolase homologs in Strongylocentrotus purpuratus suggest a gene duplication event and subsequent divergence.Diversity and biocatalytic potential of epoxide hydrolases identified by genome analysis.Detoxication strategy of epoxide hydrolase-the basis for a novel threshold for definable genotoxic carcinogensHuman soluble epoxide hydrolase: structural basis of inhibition by 4-(3-cyclohexylureido)-carboxylic acidsStereochemical features of the hydrolysis of 9,10-epoxystearic acid catalysed by plant and mammalian epoxide hydrolases.Determinants of reactivity and selectivity in soluble epoxide hydrolase from quantum mechanics/molecular mechanics modeling.Purification and characterization of a cis-epoxysuccinic acid hydrolase from Nocardia tartaricans CAS-52, and expression in Escherichia coli.Cloning and molecular characterization of a soluble epoxide hydrolase from Aspergillus niger that is related to mammalian microsomal epoxide hydrolase.Purification and characterization of a highly enantioselective epoxide hydrolase from Aspergillus niger.Primary structure and catalytic mechanism of the epoxide hydrolase from Agrobacterium radiobacter AD1.Identification and characterization of an ovary-selective isoform of epoxide hydrolase.A QM/MM MD study of the pH-dependent ring-opening catalysis and lid motif flexibility in glucosamine 6-phosphate deaminase.
P2860
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P2860
Asp333, Asp495, and His523 form the catalytic triad of rat soluble epoxide hydrolase.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Asp333, Asp495, and His523 form the catalytic triad of rat soluble epoxide hydrolase.
@en
type
label
Asp333, Asp495, and His523 form the catalytic triad of rat soluble epoxide hydrolase.
@en
prefLabel
Asp333, Asp495, and His523 form the catalytic triad of rat soluble epoxide hydrolase.
@en
P2093
P2860
P356
P1476
Asp333, Asp495, and His523 form the catalytic triad of rat soluble epoxide hydrolase.
@en
P2093
P2860
P304
P356
10.1074/JBC.271.8.4223
P407
P577
1996-02-01T00:00:00Z