Specificity of the basic side chains of Lys114, Lys125, and Arg129 of antithrombin in heparin binding.
about
Histidine-rich glycoprotein binds to cell-surface heparan sulfate via its N-terminal domain following Zn2+ chelationMolecular mapping of the thrombin-heparin cofactor II complexA Simple Method for Discovering Druggable, Specific Glycosaminoglycan-Protein Systems. Elucidation of Key Principles from Heparin/Heparan Sulfate-Binding ProteinsFinding a needle in a haystack: development of a combinatorial virtual screening approach for identifying high specificity heparin/heparan sulfate sequence(s).On the specificity of heparin/heparan sulfate binding to proteins. Anion-binding sites on antithrombin and thrombin are fundamentally different.Antithrombin regulates matriptase activity involved in plasmin generation, syndecan shedding, and HGF activation in keratinocytes.Heparin-binding domains in vascular biology.Heparanase Activates Antithrombin through the Binding to Its Heparin Binding SiteMutation of the H-helix in antithrombin decreases heparin stimulation of protease inhibition.Mutagenesis studies toward understanding the intracellular signaling mechanism of antithrombin.De novo design of self-assembling foldamers that inhibit heparin-protein interactions.Effects of acrolein, a natural occurring aldehyde, on the anticoagulant serpin antithrombin.Allosteric activation of antithrombin is independent of charge neutralization or reversal in the heparin binding site.Prothrombotic SERPINC1 gene polymorphism may affect heparin sensitivity among different ethnicities of Chinese patients receiving heart surgery.
P2860
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P2860
Specificity of the basic side chains of Lys114, Lys125, and Arg129 of antithrombin in heparin binding.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Specificity of the basic side ...... tithrombin in heparin binding.
@en
type
label
Specificity of the basic side ...... tithrombin in heparin binding.
@en
prefLabel
Specificity of the basic side ...... tithrombin in heparin binding.
@en
P2093
P356
P1433
P1476
Specificity of the basic side ...... ntithrombin in heparin binding
@en
P2093
Ingemar Björk
Steven T Olson
Susan C Bock
P304
12369-12376
P356
10.1021/BI020406J
P407
P577
2002-10-01T00:00:00Z