RNA interference of signal peptide-binding protein SRP54 elicits deleterious effects and protein sorting defects in trypanosomes.
about
Spliced leader RNA silencing (SLS) - a programmed cell death pathway in Trypanosoma brucei that is induced upon ER stressThe trypanosomatid signal recognition particle consists of two RNA molecules, a 7SL RNA homologue and a novel tRNA-like moleculeCAR-1, a protein that localizes with the mRNA decapping component DCAP-1, is required for cytokinesis and ER organization in Caenorhabditis elegans embryos.Persistent ER stress induces the spliced leader RNA silencing pathway (SLS), leading to programmed cell death in Trypanosoma brucei.Differential regulation of the TRAIL death receptors DR4 and DR5 by the signal recognition particleDown-regulation of the trypanosomatid signal recognition particle affects the biogenesis of polytopic membrane proteins but not of signal peptide-containing proteins.Scanning electron microscopy of cells and tissues under fully hydrated conditions.Post-translational import of protein into the endoplasmic reticulum of a trypanosome: an in vitro system for discovery of anti-trypanosomal chemical entities.Life and times: synthesis, trafficking, and evolution of VSG.The response of trypanosomes and other eukaryotes to ER stress and the spliced leader RNA silencing (SLS) pathway in Trypanosoma brucei.Ablation of a small transmembrane protein of Trypanosoma brucei (TbVTC1) involved in the synthesis of polyphosphate alters acidocalcisome biogenesis and function, and leads to a cytokinesis defect.Analyzing mRNA localization to the endoplasmic reticulum via cell fractionation.Spliced-leader RNA silencing: a novel stress-induced mechanism in Trypanosoma brucei.Control and regulation of gene expression: quantitative analysis of the expression of phosphoglycerate kinase in bloodstream form Trypanosoma brucei.
P2860
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P2860
RNA interference of signal peptide-binding protein SRP54 elicits deleterious effects and protein sorting defects in trypanosomes.
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年学术文章
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name
RNA interference of signal pep ...... rting defects in trypanosomes.
@en
type
label
RNA interference of signal pep ...... rting defects in trypanosomes.
@en
prefLabel
RNA interference of signal pep ...... rting defects in trypanosomes.
@en
P2093
P2860
P356
P1476
RNA interference of signal pep ...... rting defects in trypanosomes.
@en
P2093
Elisabetta Ullu
Shai Uliel
Shulamit Michaeli
Xue-hai Liang
P2860
P304
47348-47357
P356
10.1074/JBC.M207736200
P407
P577
2002-09-19T00:00:00Z