Smad pathway is activated in the diabetic mouse kidney and Smad3 mediates TGF-beta-induced fibronectin in mesangial cells.
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Smads as therapeutic targets for chronic kidney diseaseUltrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney.NAD(P)H oxidase mediates TGF-beta1-induced activation of kidney myofibroblasts.Fate-determining mechanisms in epithelial-myofibroblast transition: major inhibitory role for Smad3The effects of the water-extraction of Astragali Radix and Lycopi herba on the Pathway of TGF-smads-UPP in a rat model of Diabetic Nephropathy.Angiotensin(1-7) attenuates the progression of streptozotocin-induced diabetic renal injury better than angiotensin receptor blockade.Estrogen and raloxifene, a selective estrogen receptor modulator, ameliorate renal damage in db/db miceSmad3 deficiency ameliorates experimental obliterative bronchiolitis in a heterotopic tracheal transplantation modelMicrovascular basement membranes in diabetes mellitus.17beta-Estradiol attenuates diabetic kidney disease by regulating extracellular matrix and transforming growth factor-beta protein expression and signalingAMP-activated protein kinase (AMPK) activation inhibits nuclear translocation of Smad4 in mesangial cells and diabetic kidneys.Activin Receptor-Like Kinase 5 Inhibitor Attenuates Fibrosis in Fibroblasts Derived from Peyronie's Plaque.Smad3 as a mediator of the fibrotic response.Kidney glycosphingolipids are elevated early in diabetic nephropathy and mediate hypertrophy of mesangial cellsIncreased urinary Smad3 is significantly correlated with glomerular hyperfiltration and a reduced glomerular filtration rate and is a new urinary biomarker for diabetic nephropathy.Ethanol (EtOH)-induced TGF-β1 and reactive oxygen species production are necessary for EtOH-induced alveolar macrophage dysfunction and induction of alternative activationRole of upstream stimulatory factor 2 in diabetic nephropathy.Therapeutic strategies against TGF-beta signaling pathway in hepatic fibrosis.IHG-1 amplifies TGF-beta1 signaling and is increased in renal fibrosis.Calreticulin regulates transforming growth factor-β-stimulated extracellular matrix production.Blockade of KCa3.1 ameliorates renal fibrosis through the TGF-β1/Smad pathway in diabetic miceComplex temporal changes in TGFβ oncogenic signaling drive thyroid carcinogenesis in a mouse modelAllelic depletion of grem1 attenuates diabetic kidney disease.Essential role of TGF-beta signaling in glucose-induced cell hypertrophy.Evolution history of duplicated smad3 genes in teleost: insights from Japanese flounder, Paralichthys olivaceusEndothelial-myofibroblast transition contributes to the early development of diabetic renal interstitial fibrosis in streptozotocin-induced diabetic mice.Diverse roles of TGF-β/Smads in renal fibrosis and inflammation.Transforming growth factor-β/Smad signalling in diabetic nephropathy.TG-interacting factor is required for the differentiation of preadipocytes.Glycated albumin activates PAI-1 transcription through Smad DNA binding sites in mesangial cells.Melittin inhibits TGF-β-induced pro-fibrotic gene expression through the suppression of the TGFβRII-Smad, ERK1/2 and JNK-mediated signaling pathway.STORE OPERATED CALCIUM ENTRY SUPPRESSED TGFβ1-SMAD3 SIGNALING PATHWAY IN GLOMERULAR MESANGIAL CELLS.The expression of Smad signaling pathway in myocardium and potential therapeutic effects.Transforming Growth Factor β1 Function in Airway Remodeling and Hyperresponsiveness. The Missing Link?MiRNA-200b represses transforming growth factor-β1-induced EMT and fibronectin expression in kidney proximal tubular cells.Ruboxistaurin attenuates diabetic nephropathy via modulation of TGF-β1/Smad and GRAP pathways.TGFbeta-induced RhoA activation and fibronectin production in mesangial cells require caveolae.Psoralea corylifolia L. Seed Extract Attenuates Diabetic Nephropathy by Inhibiting Renal Fibrosis and Apoptosis in Streptozotocin-Induced Diabetic Mice.MicroRNA-196a/b Mitigate Renal Fibrosis by Targeting TGF-β Receptor 2Gremlin activates the Smad pathway linked to epithelial mesenchymal transdifferentiation in cultured tubular epithelial cells.
P2860
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P2860
Smad pathway is activated in the diabetic mouse kidney and Smad3 mediates TGF-beta-induced fibronectin in mesangial cells.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Smad pathway is activated in t ...... ibronectin in mesangial cells.
@en
type
label
Smad pathway is activated in t ...... ibronectin in mesangial cells.
@en
prefLabel
Smad pathway is activated in t ...... ibronectin in mesangial cells.
@en
P2093
P1476
Smad pathway is activated in t ...... ibronectin in mesangial cells.
@en
P2093
Fuad N Ziyadeh
M Carmen Iglesias-de la Cruz
Motohide Isono
Sheldon Chen
Soon Won Hong
P304
P356
10.1016/S0006-291X(02)02084-3
P407
P577
2002-09-01T00:00:00Z