Nuclear ADP-Ribosylation and Its Role in Chromatin Plasticity, Cell Differentiation, and Epigenetics.
about
Functions of PARylation in DNA Damage Repair PathwaysReaders of poly(ADP-ribose): designed to be fit for purposeUnderstanding specific functions of PARP-2: new lessons for cancer therapyUse of poly ADP-ribose polymerase [PARP] inhibitors in cancer cells bearing DDR defects: the rationale for their inclusion in the clinicAnalyzing structure-function relationships of artificial and cancer-associated PARP1 variants by reconstituting TALEN-generated HeLa PARP1 knock-out cells.NAD+ loss, a new player in AhR biology: prevention of thymus atrophy and hepatosteatosis by NAD+ repletion.ARTD1 regulates osteoclastogenesis and bone homeostasis by dampening NF-κB-dependent transcription of IL-1βADPriboDB: The database of ADP-ribosylated proteins.Serine is a new target residue for endogenous ADP-ribosylation on histones.Insight into the machinery that oils chromatin dynamics.ADP-Ribosylated Peptide Enrichment and Site Identification: The Phosphodiesterase-Based Method.The conserved macrodomains of the non-structural proteins of Chikungunya virus and other pathogenic positive strand RNA viruses function as mono-ADP-ribosylhydrolases.At the Interface of Three Nucleic Acids: The Role of RNA-Binding Proteins and Poly(ADP-ribose) in DNA Repair.Chemical genetic discovery of PARP targets reveals a role for PARP-1 in transcription elongation.Serine ADP-ribosylation reversal by the hydrolase ARH3Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9.Downregulation of PARP1 transcription by promoter-associated E2F4-RBL2-HDAC1-BRM complex contributes to repression of pluripotency stem cell factors in human monocytesDiscovery of a selective allosteric inhibitor targeting macrodomain 2 of poly-adenosine-diphosphate-ribose polymerases 14.Common and unique genetic interactions of the poly(ADP-ribose) polymerases PARP1 and PARP2 with DNA double-strand break repair pathways.PARP1-produced poly-ADP-ribose causes the PARP12 translocation to stress granules and impairment of Golgi complex functions.Oxidative stress rapidly stabilizes promoter-proximal paused Pol II across the human genome.Proteomic analyses identify ARH3 as a serine mono-ADP-ribosylhydrolase.The role of poly ADP-ribosylation in the first wave of DNA damage response.ADP-ribosylation of DNA moving into focus.PARP1 protects from benzo[a]pyrene diol epoxide-induced replication stress and mutagenicity.Heritable Sperm Chromatin Epigenetics: A Break to Remember.Specificity of reversible ADP-ribosylation and regulation of cellular processes.ADP-ribosyl-N₃: A Versatile Precursor for Divergent Syntheses of ADP-ribosylated Compounds.Characterization of DNA ADP-ribosyltransferase activities of PARP2 and PARP3: new insights into DNA ADP-ribosylation.ADP-ribose-specific chromatin-affinity purification for investigating genome-wide or locus-specific chromatin ADP-ribosylation.Measurement of drug-target engagement in live cells by two-photon fluorescence anisotropy imaging.Proteomic Analysis of the Downstream Signaling Network of PARP1.Catalytic-Independent Functions of PARP-1 Determine Sox2 Pioneer Activity at Intractable Genomic Loci.PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation.Cell Cycle Resolved Measurements of Poly(ADP-Ribose) Formation and DNA Damage Signaling by Quantitative Image-Based Cytometry.Role of novel histone modifications in cancer.Dna is a New Target of Parp3.Comparative inhibitory profile and distribution of bacterial PARPs, using Clostridioides difficile CD160 PARP as a model.Nucleolar-nucleoplasmic shuttling of TARG1 and its control by DNA damage-induced poly-ADP-ribosylation and by nucleolar transcription.Comprehensive ADP-ribosylome analysis identifies tyrosine as an ADP-ribose acceptor site
P2860
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P2860
Nuclear ADP-Ribosylation and Its Role in Chromatin Plasticity, Cell Differentiation, and Epigenetics.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
Nuclear ADP-Ribosylation and I ...... ferentiation, and Epigenetics.
@en
type
label
Nuclear ADP-Ribosylation and I ...... ferentiation, and Epigenetics.
@en
prefLabel
Nuclear ADP-Ribosylation and I ...... ferentiation, and Epigenetics.
@en
P1476
Nuclear ADP-Ribosylation and I ...... fferentiation, and Epigenetics
@en
P2093
Michael O Hottiger
P304
P356
10.1146/ANNUREV-BIOCHEM-060614-034506
P577
2015-02-26T00:00:00Z