The ever-expanding immunomodulatory role of calreticulin in cancer immunity - Wikidata - wikimedia - TriplyDB

The ever-expanding immunomodulatory role of calreticulin in cancer immunity

The ever-expanding immunomodulatory role of calreticulin in cancer immunity

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Concepts and mechanisms underlying chemotherapy induced immunogenic cell death: impact on clinical studies and considerations for combined therapies Calreticulin (CALR) mutation in myeloproliferative neoplasms (MPNs)Structures of parasite calreticulins provide insights into their flexibility and dual carbohydrate/peptide-binding properties.Algenpantucel-L immunotherapy in pancreatic adenocarcinoma.Calreticulin, a therapeutic target?Programmed cell removal biomarkers calreticulin and CD47 implicated in oral lichen planus.Pancreatic cancer: Update on immunotherapies and algenpantucel-L.Editorial: Endoplasmic Reticulum and Its Role in Tumor Immunity.Calreticulin as a novel B-cell receptor antigen in chronic lymphocytic leukemia.Critical Interactions between Immunogenic Cancer Cell Death, Oncolytic Viruses, and the Immune System Define the Rational Design of Combination Immunotherapies.Molecular and Biochemical Characterization of Opisthorchis viverrini Calreticulin.Harnessing the Power of Invariant Natural Killer T Cells in Cancer Immunotherapy.Expression and significance of calreticulin in human osteosarcoma.Cancer Cell Death-Inducing Radiotherapy: Impact on Local Tumour Control, Tumour Cell Proliferation and Induction of Systemic Anti-tumour Immunity.

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The ever-expanding immunomodulatory role of calreticulin in cancer immunity

http://www.wikidata.org/entity/Q38370365

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2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年學術文章

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2015年學術文章

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2015年學術文章

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The ever-expanding immunomodulatory role of calreticulin in cancer immunity

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The ever-expanding immunomodulatory role of calreticulin in cancer immunity

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FONC.2015.00035

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Frontiers in Oncology

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The ever-expanding immunomodulatory role of calreticulin in cancer immunity

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Marco de Bruyn

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Valerie R Wiersma

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Wijnand Helfrich

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P2860

Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47

A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death

CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis

Calreticulin exposure dictates the immunogenicity of cancer cell death

Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte

Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

Immunogenic and tolerogenic cell death.

Extracellular calreticulin is present in the joints of patients with rheumatoid arthritis and inhibits FasL (CD95L)-mediated apoptosis of T cells.

Immunogenic cell death and DAMPs in cancer therapy.

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35

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scholarly article

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10.3389/FONC.2015.00035

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