Cardiac Myocyte-specific Knock-out of Calcium-independent Phospholipase A2γ (iPLA2γ) Decreases Oxidized Fatty Acids during Ischemia/Reperfusion and Reduces Infarct Size.
about
The phospholipase iPLA2γ is a major mediator releasing oxidized aliphatic chains from cardiolipin, integrating mitochondrial bioenergetics and signaling.Antioxidant tempol suppresses heart cytosolic phospholipase A2α stimulated by chronic intermittent hypoxia.Heart failure-induced activation of phospholipase iPLA2γ generates hydroxyeicosatetraenoic acids opening the mitochondrial permeability transition pore.Mitochondrial uncoupling proteins: subtle regulators of cellular redox signaling."HETE"ing up mitochondria in human heart failure.
P2860
Cardiac Myocyte-specific Knock-out of Calcium-independent Phospholipase A2γ (iPLA2γ) Decreases Oxidized Fatty Acids during Ischemia/Reperfusion and Reduces Infarct Size.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Cardiac Myocyte-specific Knock ...... sion and Reduces Infarct Size.
@en
type
label
Cardiac Myocyte-specific Knock ...... sion and Reduces Infarct Size.
@en
prefLabel
Cardiac Myocyte-specific Knock ...... sion and Reduces Infarct Size.
@en
P2093
P2860
P356
P1476
Cardiac Myocyte-specific Knock ...... sion and Reduces Infarct Size.
@en
P2093
Annie L Nguyen
Attila Kovacs
Beverly Gibson Dilthey
Carla J Weinheimer
Christopher M Jenkins
Dana Abendschein
David J Mancuso
Harold F Sims
Richard W Gross
P2860
P304
19687-19700
P356
10.1074/JBC.M116.740597
P407
P577
2016-07-23T00:00:00Z