Phase II study to assess the efficacy, safety and tolerability of the mitotic spindle kinesin inhibitor AZD4877 in patients with recurrent advanced urothelial cancer.
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Targeting the Mitotic Catastrophe Signaling Pathway in CancerLoss-of-Function Mutations in KIF15 Underlying a Braddock-Carey Genocopy.Multimodal effects of small molecule ROCK and LIMK inhibitors on mitosis, and their implication as anti-leukemia agents.Eg5 inhibitor, a novel potent targeted therapy, induces cell apoptosis in renal cell carcinoma.Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors.Two Phase 1 dose-escalation studies exploring multiple regimens of litronesib (LY2523355), an Eg5 inhibitor, in patients with advanced cancer.A New Way to Treat Brain Tumors: Targeting Proteins Coded by Microcephaly Genes?: Brain tumors and microcephaly arise from opposing derangements regulating progenitor growth. Drivers of microcephaly could be attractive brain tumor targets.
P2860
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P2860
Phase II study to assess the efficacy, safety and tolerability of the mitotic spindle kinesin inhibitor AZD4877 in patients with recurrent advanced urothelial cancer.
description
2013 nî lūn-bûn
@nan
2013年の論文
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2013年論文
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2013年論文
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2013年論文
@zh-hk
2013年論文
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2013年論文
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2013年论文
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2013年论文
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2013年论文
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name
Phase II study to assess the e ...... nt advanced urothelial cancer.
@en
type
label
Phase II study to assess the e ...... nt advanced urothelial cancer.
@en
prefLabel
Phase II study to assess the e ...... nt advanced urothelial cancer.
@en
P2093
P2860
P1476
Phase II study to assess the e ...... nt advanced urothelial cancer.
@en
P2093
Anna Osmukhina
Arkadiusz Z Dudek
Christian Wülfing
Gary Hudes
Graham Mead
Jacqueline Vuky
Jeffrey Skolnik
Jianguo Li
John Chester
José Angel Arranz
P2860
P2888
P304
P356
10.1007/S10637-013-9926-Y
P577
2013-01-18T00:00:00Z
P6179
1048652387