A designer bleomycin with significantly improved DNA cleavage activity.
about
Expression of the platencin biosynthetic gene cluster in heterologous hosts yielding new platencin congeners.Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update for 2011-2012.Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892BlmB and TlmB provide resistance to the bleomycin family of antitumor antibiotics by N-acetylating metal-free bleomycin, tallysomycin, phleomycin, and zorbamycin.The determination of the DNA sequence specificity of bleomycin-induced abasic sites.A comprehensive review of glycosylated bacterial natural products.Adaptation of the neutral bacterial comet assay to assess antimicrobial-mediated DNA double-strand breaks in Escherichia coli.Engineered production and evaluation of 6'-deoxy-tallysomycin H-1 revealing new insights into the structure-activity relationship of the anticancer drug bleomycin.A novel application of radiomimetic compounds as antibiotic drugs.The paired receptors TIGIT and DNAM-1 as targets for therapeutic antibodies.Zorbamycin has a different DNA sequence selectivity compared with bleomycin and analogues.Strain improvement by combined UV mutagenesis and ribosome engineering and subsequent fermentation optimization for enhanced 6'-deoxy-bleomycin Z production.The Interaction of the Metallo-Glycopeptide Anti-Tumour Drug Bleomycin with DNA.
P2860
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P2860
A designer bleomycin with significantly improved DNA cleavage activity.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
A designer bleomycin with significantly improved DNA cleavage activity.
@en
type
label
A designer bleomycin with significantly improved DNA cleavage activity.
@en
prefLabel
A designer bleomycin with significantly improved DNA cleavage activity.
@en
P2093
P2860
P356
P1476
A designer bleomycin with significantly improved DNA cleavage activity
@en
P2093
Evelyn Wendt-Pienkowski
Jane M Coughlin
Liyan Wang
Meifeng Tao
Sheng-Xiong Huang
Yanwen Duan
Zhiyang Feng
P2860
P304
13501-13509
P356
10.1021/JA3056535
P407
P50
P577
2012-08-06T00:00:00Z