Ascending single-dose study of the safety profile, tolerability, and pharmacokinetics of bosutinib coadministered with ketoconazole to healthy adult subjects.
about
Ketoconazole-Associated Liver Injury in Drug-Drug Interaction Studies in Healthy Volunteers.Clinical Pharmacokinetics and Pharmacodynamics of Bosutinib.Pharmacokinetic drug-drug interactions of tyrosine kinase inhibitors: A focus on cytochrome P450, transporters, and acid suppression therapy.Effects of ketoconazole on cyclophosphamide metabolism: evaluation of CYP3A4 inhibition effect using the in vitro and in vivo models.Practical Management of Toxicities Associated With Bosutinib in Patients With Philadelphia Chromosome-Positive Chronic Myeloid Leukemia.Effect of aprepitant, a moderate CYP3A4 inhibitor, on bosutinib exposure in healthy subjects.Clinical Drug-Drug Interactions Through Cytochrome P450 3A (CYP3A) for the Selective ALK Inhibitor Alectinib.
P2860
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P2860
Ascending single-dose study of the safety profile, tolerability, and pharmacokinetics of bosutinib coadministered with ketoconazole to healthy adult subjects.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Ascending single-dose study of ...... ole to healthy adult subjects.
@en
type
label
Ascending single-dose study of ...... ole to healthy adult subjects.
@en
prefLabel
Ascending single-dose study of ...... ole to healthy adult subjects.
@en
P2093
P1476
Ascending single-dose study of ...... ole to healthy adult subjects.
@en
P2093
Cathie Leister
Daryl Sonnichsen
Myriam El Gaaloul
Richat Abbas
Stephan Chalon
P304
P356
10.1016/J.CLINTHERA.2012.07.006
P577
2012-08-09T00:00:00Z