Sec62p, a component of the endoplasmic reticulum protein translocation machinery, contains multiple binding sites for the Sec-complex
about
Structural studies and the assembly of the heptameric post-translational translocon complexIdentification of novel protein-protein interactions at the cytosolic surface of the Sec63 complex in the yeast ER membrane.Recognition of a subset of signal sequences by Ssh1p, a Sec61p-related protein in the membrane of endoplasmic reticulum of yeast Saccharomyces cerevisiae.Evolutionary gain of function for the ER membrane protein Sec62 from yeast to humansTargeting cell migration and the endoplasmic reticulum stress response with calmodulin antagonists: a clinically tested small molecule phenocopy of SEC62 gene silencing in human tumor cells.Aberrant substrate engagement of the ER translocon triggers degradation by the Hrd1 ubiquitin ligase.Mutation of sec63 in zebrafish causes defects in myelinated axons and liver pathologyProtein translocation across the rough endoplasmic reticulum.Sec62 protein mediates membrane insertion and orientation of moderately hydrophobic signal anchor proteins in the endoplasmic reticulum (ER)Split-ubiquitin and the split-protein sensors: chessman for the endgame.The Sec translocon mediated protein transport in prokaryotes and eukaryotes.The Brl domain in Sec63p is required for assembly of functional endoplasmic reticulum translocons.The Sec63p J-domain is required for ERAD of soluble proteins in yeast.Efficient protein depletion by genetically controlled deprotection of a dormant N-degron.
P2860
Q27930101-5718FFD8-B9A3-47C2-A802-B8315FE2D5BEQ27932057-1682BF4F-4857-4B46-B26F-86F4B9D1A8C0Q27939668-1F496BF7-3865-44CA-BED4-33F4EAE693AEQ33689768-2B364357-41DC-4204-990A-4C7CFE1A908DQ35058949-E608DBEA-68F6-4B52-ADDA-A12E69F7DFBDQ36027390-DF7D6A1D-B06F-483A-8C15-CCA91686C0C3Q36486029-3D013320-7394-4FA9-BAAC-0600A81F7E4BQ36555178-9D2AE8D9-308C-40E2-BA5E-CBEDB0C2FE8EQ36947743-F8415A09-0A47-429F-8547-A088613C8CB5Q37234585-181ADE27-5C6B-4D52-AD04-59BE3E8ACF7BQ38206834-1C59B752-FEE7-4668-ACB8-F84B676A271DQ38317482-0654F91D-AB2B-4010-A7AB-F12184CB09BBQ42842073-5B4AF1E6-E852-4A66-9B1F-30B80F0379CDQ43125305-FE20DB8A-23BD-4887-9923-366ACE2CEC84
P2860
Sec62p, a component of the endoplasmic reticulum protein translocation machinery, contains multiple binding sites for the Sec-complex
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Sec62p, a component of the end ...... ding sites for the Sec-complex
@en
type
label
Sec62p, a component of the end ...... ding sites for the Sec-complex
@en
prefLabel
Sec62p, a component of the end ...... ding sites for the Sec-complex
@en
P2093
P2860
P356
P1476
Sec62p, a component of the end ...... ding sites for the Sec-complex
@en
P2093
P2860
P304
P356
10.1091/MBC.11.11.3859
P577
2000-11-01T00:00:00Z