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Induced pluripotency and oncogenic transformation are related processes.

Induced pluripotency and oncogenic transformation are related processes.

http://www.wikidata.org/entity/Q38494976

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Induced Pluripotency and Gene Editing in Disease Modelling: Perspectives and Challenges Immunogenicity and tumorigenicity of pluripotent stem cells and their derivatives: genetic and epigenetic perspectives Cell therapy for heart failure: a comprehensive overview of experimental and clinical studies, current challenges, and future directions Metabolic control of cancer cell stemness: Lessons from iPS cells Challenges in identifying the best source of stem cells for cardiac regeneration therapy Induced pluripotent stem cells show metabolomic differences to embryonic stem cells in polyunsaturated phosphatidylcholines and primary metabolism Identification of DPPA4 and DPPA2 as a novel family of pluripotency-related oncogenes.Somatic polyploidy is associated with the upregulation of c-MYC interacting genes and EMT-like signature The Dual Roles of MYC in Genomic Instability and Cancer Chemoresistance A human pluripotent stem cell surface N-glycoproteome resource reveals markers, extracellular epitopes, and drug targets.The nutritional phenome of EMT-induced cancer stem-like cells p53: the barrier to cancer stem cell formation.The Activation of the Sox2 RR2 Pluripotency Transcriptional Reporter in Human Breast Cancer Cell Lines is Dynamic and Labels Cells with Higher Tumorigenic Potential.Deregulated proliferation and differentiation in brain tumors.Scientists: you really need to get out of the lab more "Second-generation" stem cells for cardiac repair Immunoreactivity of Pluripotent Markers SSEA-5 and L1CAM in Human Tumors, Teratomas, and Induced Pluripotent Stem Cells Mesenchymal stem cell therapy for doxorubicin cardiomyopathy: hopes and fears A Tox21 Approach to Altered Epigenetic Landscapes: Assessing Epigenetic Toxicity Pathways Leading to Altered Gene Expression and Oncogenic Transformation In Vitro Stalling the engine of resistance: targeting cancer metabolism to overcome therapeutic resistance.Analysis of induced pluripotent stem cells from a BRCA1 mutant family.Nuclear reprogramming of luminal-like breast cancer cells generates Sox2-overexpressing cancer stem-like cellular states harboring transcriptional activation of the mTOR pathway.The mitochondrial H(+)-ATP synthase and the lipogenic switch: new core components of metabolic reprogramming in induced pluripotent stem (iPS) cells.Epigenetic memory in the context of nuclear reprogramming and cancer.Current tissue engineering strategies in anterior cruciate ligament reconstruction.In vivo reprogramming in inflammatory bowel disease.Histone H3.3 mutations: a variant path to cancer.Epigenetic mechanisms of tumorigenicity manifesting in stem cells.Behavior of Xeno-Transplanted Undifferentiated Human Induced Pluripotent Stem Cells Is Impacted by Microenvironment Without Evidence of Tumors.Transplantation of human villous trophoblasts preserves cardiac function in mice with acute myocardial infarction.Modeling the autistic cell: iPSCs recapitulate developmental principles of syndromic and nonsyndromic ASD.Stem cells and diabetic cardiomyopathy: from pathology to therapy.Stem Cell Therapy: A New Therapeutic Option for Cardiovascular Diseases.PRG3 induces Ras-dependent oncogenic cooperation in gliomas.The Warburg effect version 2.0: metabolic reprogramming of cancer stem cells.Linking Pluripotency Reprogramming and Cancer ERBB3-Binding Protein 1 (EBP1) Is a Novel Developmental Pluripotency-Associated-4 (DPPA4) Cofactor in Human Pluripotent Cells.While it is not deliberate, much of today's biomedical research contains logical and technical flaws, showing a need for corrective action.Stem cell therapy targeting the right ventricle in pulmonary arterial hypertension: is it a potential avenue of therapy?

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P2860

Induced pluripotency and oncogenic transformation are related processes.

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Stem Cells and Development

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Bonnie L Barrilleaux

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John W Riggs

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Kelly M Bush

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Natasha Varlakhanova

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P2860

myc maintains embryonic stem cell pluripotency and self-renewal

Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine

STRING 8--a global view on proteins and their functional interactions in 630 organisms

N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor

Induced pluripotent stem cell lines derived from human somatic cells

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

Generation of germline-competent induced pluripotent stem cells

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells

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