Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation.
about
Hematopoietic stem cell development, niches, and signaling pathwaysWnt signaling promotes hematoendothelial cell development from human embryonic stem cellsWnt signaling: the good and the badGlycogen synthase kinase-3β is a pivotal mediator of cancer invasion and resistance to therapyWnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia developmentImproving cell-based therapies by nanomodificationGenetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regenerationCellular plasticity cascades in the pathophysiology and treatment of bipolar disorderCancer stem cells: the lessons from pre-cancerous stem cellsA critical role for Apc in hematopoietic stem and progenitor cell survivalActivation of Wnt/β-catenin protein signaling induces mitochondria-mediated apoptosis in hematopoietic progenitor cellsDiscovering chemical modifiers of oncogene-regulated hematopoietic differentiationLithium chloride regulates the proliferation of stem-like cells in retinoblastoma cell lines: a potential role for the canonical Wnt signaling pathway.Small molecule p300/catenin antagonist enhances hematopoietic recovery after radiation.Sonic hedgehog expands diaphyseal trabecular bone altering bone marrow niche and lymphocyte compartment.The Apc(min) mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS.Inhibiting glycogen synthase kinase-3 mitigates the hematopoietic acute radiation syndrome in miceSulfatase modifying factor 1-mediated fibroblast growth factor signaling primes hematopoietic multilineage development.Therapeutic cell engineering with surface-conjugated synthetic nanoparticles.Downregulation of GSK3β by miR-544a to maintain self-renewal ability of lung caner stem cells.The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia.Progeroid syndromes: models for stem cell aging?Wnt-related molecules and signaling pathway equilibrium in hematopoiesis.Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo.Role of casein kinase 1A1 in the biology and targeted therapy of del(5q) MDS.Aberrant glycogen synthase kinase 3β is involved in pancreatic cancer cell invasion and resistance to therapy.ON01210.Na (Ex-RAD®) mitigates radiation damage through activation of the AKT pathway.Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction.Ex vivo expansion of human hematopoietic stem and progenitor cells.Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regenerationProstaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models.Wnt-inhibitory factor 1 dysregulation of the bone marrow niche exhausts hematopoietic stem cells.Wnt3a protein reduces growth factor-driven expansion of human hematopoietic stem and progenitor cells in serum-free cultures.Generation of a lentiviral vector producer cell clone for human Wiskott-Aldrich syndrome gene therapy.Glycogen synthase kinase-3β promotes cyst expansion in polycystic kidney diseaseSmall-molecule inhibitors targeting INK4 protein p18(INK4C) enhance ex vivo expansion of haematopoietic stem cells.Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulationWnts are dispensable for differentiation and self-renewal of adult murine hematopoietic stem cells.Distinct gene expression program dynamics during erythropoiesis from human induced pluripotent stem cells compared with adult and cord blood progenitors.Specific deletion of glycogen synthase kinase-3β in the renal proximal tubule protects against acute nephrotoxic injury in mice
P2860
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P2860
Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Glycogen synthase kinase-3 is ...... oietic stem cell repopulation.
@en
type
label
Glycogen synthase kinase-3 is ...... oietic stem cell repopulation.
@en
prefLabel
Glycogen synthase kinase-3 is ...... oietic stem cell repopulation.
@en
P2093
P2860
P356
P1433
P1476
Glycogen synthase kinase-3 is ...... oietic stem cell repopulation.
@en
P2093
Anargyros Xenocostas
Jennifer J Trowbridge
Mickie Bhatia
Randall T Moon
P2860
P2888
P356
10.1038/NM1339
P407
P577
2005-12-11T00:00:00Z
P6179
1041739053