The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections. - Wikidata - wikimedia - TriplyDB

The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections.

The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections.

http://www.wikidata.org/entity/Q38514365

about

Viral Inhibition of the IFN-Induced JAK/STAT Signalling Pathway: Development of Live Attenuated Vaccines by Mutation of Viral-Encoded IFN-Antagonists Interferon-λ: Immune Functions at Barrier Surfaces and Beyond IFN-λ: A New Inducer of Local Immunity against Cancer and Infections Interferons and viruses: an evolutionary arms race of molecular interactions Mumps Virus Induces Protein-Kinase-R-Dependent Stress Granules, Partly Suppressing Type III Interferon Production.Interference of retroviral envelope with vaccine-induced CD8+ T cell responses is relieved by co-administration of cytokine-encoding vectors.Interferon lambda: opportunities, risks, and uncertainties in the fight against HCV.IL-28B is a key regulator of B- and T-cell vaccine responses against influenza Enterovirus-infected β-cells induce distinct response patterns in BDCA1+ and BDCA3+ human dendritic cells.Type I Interferons Direct Gammaherpesvirus Host Colonization The Effect of Chronic Hepatitis B Virus Infection on BDCA3+ Dendritic Cell Frequency and Function.The Role of Hepatitis C Virus Core Antigen Testing in the Era of Direct Acting Antiviral Therapies: What We Can Learn from the Protease Inhibitors Design and evaluation of novel interferon lambda analogs with enhanced antiviral activity and improved drug attributes.Update on macrophages and innate immunity in scleroderma Antiviral Activities of Different Interferon Types and Subtypes against Hepatitis E Virus Replication.Impact of host genetic polymorphisms on vaccine induced antibody response Protozoan Parasites and Type I IFNs.A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection.Interferon Lambda: Modulating Immunity in Infectious Diseases.Type III Interferon-Mediated Signaling Is Critical for Controlling Live Attenuated Yellow Fever Virus Infection In Vivo.Involvement of NK Cells in IL-28B-Mediated Immunity against Influenza Virus Infection.Expression of Ifnlr1 on Intestinal Epithelial Cells Is Critical to the Antiviral Effects of Interferon Lambda against Norovirus and Reovirus.Gene-disease association with human IFNL locus polymorphisms extends beyond hepatitis C virus infections.The Role of Type III Interferons in Hepatitis C Virus Infection and Therapy.The Impact of the Interferon/TNF-Related Apoptosis-Inducing Ligand Signaling Axis on Disease Progression in Respiratory Viral Infection and Beyond.Type 1 Diabetes and Type 1 Interferonopathies: Localization of a Type 1 Common Thread of Virus Infection in the Pancreas.Tollip SNP rs5743899 modulates human airway epithelial responses to rhinovirus infection.MicroRNA-21: A Positive Regulator for Optimal Production of Type I and Type III Interferon by Plasmacytoid Dendritic Cells.RNA-virus proteases counteracting host innate immunity.Ku70 Senses HTLV-1 DNA and Modulates HTLV-1 Replication.Differential expression of innate immune response genes in clinical phases of chronic hepatitis B infection.Endogenously produced TNF-α contributes to the expression of CXCL10/IP-10 in IFN-λ3-activated plasmacytoid dendritic cells.IFN-stimulated gene expression is independent of the IFNL4 genotype in chronic HIV-1 infection.IFNλ is a potent anti-influenza therapeutic without the inflammatory side effects of IFNα treatment.An ELISA Based Binding and Competition Method to Rapidly Determine Ligand-receptor Interactions.Type I Interferon Is a Catastrophic Feature of the Diabetic Islet Microenvironment Outcomes of Congenital Zika Disease Depend on Timing of Infection and Maternal-Fetal Interferon Action.RIG-I-like receptor activation by dengue virus drives follicular T helper cell formation and antibody production.Immune and Imaging Correlates of Mild Cognitive Impairment Conversion to Alzheimer's Disease.A Biomolecular Network Driven Proteinic Interaction in HCV Clearance.

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The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections.

http://www.wikidata.org/entity/Q38514365

description

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Adrian Egli

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D Lorne Tyrrell

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Daire O'Shea

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Deanna M Santer

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Michael Houghton

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P2860

Role of the interleukin (IL)-28 receptor tyrosine residues for antiviral and antiproliferative activity of IL-29/interferon-lambda 1: similarities with type I interferon signaling

At least three human type alpha interferons: structure of alpha 2

Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors

A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus

IFN-lambda1 (IL-29) inhibits GATA3 expression and suppresses Th2 responses in human naive and memory T cells

IL-28, IL-29 and their class II cytokine receptor IL-28R

IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex

UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity

Cloning of a new type II cytokine receptor activating signal transducer and activator of transcription (STAT)1, STAT2 and STAT3

Alpha/beta interferon (IFN-alpha/beta)-independent induction of IFN-lambda1 (interleukin-29) in response to Hantaan virus infection

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10.1038/EMI.2014.51

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