about
Linear ubiquitination prevents inflammation and regulates immune signallingThe structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and a mode of MHC class I dimerizationThe 1.5 A crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominanceA structural basis for the selection of dominant alphabeta T cell receptors in antiviral immunityA Naturally Selected Dimorphism within the HLA-B44 Supertype Alters Class I Structure, Peptide Repertoire, and T Cell RecognitionA T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I moleculeA structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac diseaseEpitope-specific TCR repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptidesStructural and biological basis of CTL escape in coronavirus-infected miceHuman leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivityPrevention of Cytotoxic T Cell Escape Using a Heteroclitic Subdominant Viral T Cell DeterminantComplete modification of TCR specificity and repertoire selection does not perturb a CD8+ T cell immunodominance hierarchyNatural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognitionThe shaping of T cell receptor recognition by self-tolerancePhosphorylated self-peptides alter human leukocyte antigen class I-restricted antigen presentation and generate tumor-specific epitopesT cell allorecognition via molecular mimicryConstraints within major histocompatibility complex class I restricted peptides: Presentation and consequences for T-cell recognitionHard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptabilityAllelic polymorphism in the T cell receptor and its impact on immune responsesProtective Efficacy of Cross-Reactive CD8+ T Cells Recognising Mutant Viral Epitopes Depends on Peptide-MHC-I Structural Interactions and T Cell Activation ThresholdThe structural basis for autonomous dimerization of the pre-T-cell antigen receptorStructural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responsesAssembly of the Type II Secretion System such as Found in Vibrio cholerae Depends on the Novel Pilotin AspSA structural basis for varied αβ TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 moleculePreemptive priming readily overcomes structure-based mechanisms of virus escapeHighly Divergent T-cell Receptor Binding Modes Underlie Specific Recognition of a Bulged Viral Peptide bound to a Human Leukocyte Antigen Class I MoleculeThe Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I MoleculeA molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritisImmune self-reactivity triggered by drug-modified HLA-peptide repertoireMR1 presents microbial vitamin B metabolites to MAIT cellsBiased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac diseaseA Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen MicropolymorphismStructural and Functional Correlates of Enhanced Antiviral Immunity Generated by Heteroclitic CD8 T Cell EpitopesHLA peptide length preferences control CD8+ T cell responsesAn extensive antigenic footprint underpins immunodominant TCR adaptability against a hypervariable viral determinantT Cell Cross-Reactivity between a Highly Immunogenic EBV Epitope and a Self-Peptide Naturally Presented by HLA-B*18:01+ CellsT cell receptor reversed polarity recognition of a self-antigen major histocompatibility complexA Naturally Occurring Peptide with an Elementary Single Disulfide-Directed β-Hairpin FoldOptimization of the MHC class I peptide cargo is dependent on tapasinImmunoproteomics: Mass spectrometry-based methods to study the targets of the immune response
P50
Q24298581-DCF87548-986F-44C3-A9BB-019FE1E23B5DQ27639867-5E8B2DFA-749B-419E-A5F2-3DBC343A1F8FQ27639950-D4F6BCA2-3CE5-4E4E-A465-9C407C1BF626Q27640322-B16E3F56-448A-4150-977A-F44ABB826AD2Q27641906-11DC5BDA-9D6E-4FBA-A5CF-55EDB56B5C91Q27643687-43F6C528-8F39-43FC-AB60-157935D5EF48Q27646673-9DB3D7AF-BB0C-4C22-AB8F-871AD0467302Q27649750-9CE716DE-A0D8-4CF4-9BBB-8BFDCC70AEFBQ27649999-C7D52C68-E85D-4D1F-AA38-4BC0C9508D07Q27650811-9520EC1C-6CBE-4FCE-A322-19E9C6BA91B6Q27652640-FD243E8D-23D8-4965-90B9-10EBB3E4AFCEQ27653021-EB871A3E-90CE-48DF-82F2-84AD49730D5CQ27653404-3B29B596-EC65-4687-A37B-23F22CF628BAQ27653508-7D8C2F2A-A0AB-4D11-ADBB-2FBA850A700DQ27653670-53E58CED-5681-47CA-A94A-9F2393C596FAQ27658914-6B827D8B-8D2D-4178-A212-7803B1FD6235Q27660158-92D68D12-0070-470A-BA09-4FEBAC0F83E1Q27661747-F80A9D30-D59D-4311-BCB5-B535D66B40CFQ27662550-5CB6334D-C7F1-4E6F-AD1E-401EF6126E58Q27664060-E06B5CBB-A96F-4FB8-A10D-F53E85852ADCQ27665016-EE8BC446-604A-46D0-9F05-20E468C5AD97Q27667972-4AF0B43F-F574-4D42-908B-C84BF4D1F2CEQ27675923-13945F50-E257-4B7D-81AC-DBB0794BECB8Q27675980-BA55078A-64CC-4087-BD3C-BE723AF88646Q27676834-D3726E44-A8AB-44CC-BC02-6BC34A49D0D2Q27677256-3B7D8B2A-DE89-414B-AB44-7358BFC1F75CQ27677334-DA98232F-B5B4-454A-B716-13FE288656B5Q27680522-57F9055A-EC48-41A8-A02A-7C2ED2A77ACBQ27681301-34BC9C96-FEBE-4BF0-AB2C-05E932DE8DB8Q27682747-03948D3C-2F46-40E5-AF16-6DB99771B20DQ27682775-3FF51925-F28F-4140-AE50-22CEAD8FE1B2Q27683527-A465F858-0B19-4DE3-98F4-14FDCB5E5E82Q27683638-8D11BCE6-F69A-4E21-A4AC-CDBC3FE0EBB0Q27684796-324DA6B3-1C0C-4314-888B-D582E1944FC4Q27695801-58F490EE-F00C-4020-A5C1-EC4409275AF3Q27700158-C51AE8AA-72C5-46AC-9AAD-9FFDF7B8B6D5Q27702245-1B19C824-9447-4CB1-AEAE-B0605DB2DF4CQ27703622-8CB3FDE7-A309-4443-B731-85194BAAEEEEQ28215565-52DB27B0-4ACD-462A-8626-F95954C0D585Q28238379-2A544BAE-221F-4DDE-BCED-5D47638D826F
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Anthony W. Purcell
@ast
Anthony W. Purcell
@en
Anthony W. Purcell
@es
Anthony W. Purcell
@nl
type
label
Anthony W. Purcell
@ast
Anthony W. Purcell
@en
Anthony W. Purcell
@es
Anthony W. Purcell
@nl
prefLabel
Anthony W. Purcell
@ast
Anthony W. Purcell
@en
Anthony W. Purcell
@es
Anthony W. Purcell
@nl
P106
P1153
7005219893
P21
P31
P496
0000-0003-0532-8331