Rigidity versus flexibility: the dilemma of understanding protein thermal stability.
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Engineering a Cysteine-Free Form of Human Fibroblast Growth Factor-1 for "Second Generation" Therapeutic ApplicationHU histone-like DNA-binding protein from Thermus thermophilus: structural and evolutionary analysesDancing through Life: Molecular Dynamics Simulations and Network-Centric Modeling of Allosteric Mechanisms in Hsp70 and Hsp110 Chaperone Proteins.Exploring the thermostable properties of halohydrin dehalogenase from Agrobacterium radiobacter AD1 by a combinatorial directed evolution strategy.A complete thermodynamic analysis of enzyme turnover links the free energy landscape to enzyme catalysis.Structural and dynamic evolution of the amphipathic N-terminus diversifies enzyme thermostability in the glycoside hydrolase family 12.Shedding light on the extra thermal stability of thermophilic proteins.Role of Proteome Physical Chemistry in Cell Behavior.Rigidity and flexibility in the tetrasaccharide linker of proteoglycans from atomic-resolution molecular simulation.Side chain flexibility and coupling between the S4-S5 linker and the TRP domain in thermo-sensitive TRP channels: Insights from protein modeling.Genetic engineering of Trichoderma reesei cellulases and their production.A highly Conserved Aspartic Acid Residue of the Chitosanase from Bacillus Sp. TS Is Involved in the Substrate Binding.Spore Heat Activation Requirements and Germination Responses Correlate with Sequences of Germinant Receptors and with the Presence of a Specific spoVA2mob Operon in Foodborne Strains of Bacillus subtilis.The effect of the pathological V72I, D109N and T190M missense mutations on the molecular structure of α-dystroglycanWhat makes proteins work: exploring life in P-T-X.Thermophilic adaptation in prokaryotes is constrained by metabolic costs of proteostasis.Point mutation Arg153-His at surface of Bacillus lipase contributing towards increased thermostability and ester synthesis: insight into molecular network.From mutational inactivation to aberrant gain-of-function: Unraveling the structural basis of mutant p53 oncogenic transition.Kinetic stability of membrane proteins.Alanine mutation of the catalytic sites of Pantothenate Synthetase causes distinct conformational changes in the ATP binding region.Biomechanical defects and rescue of cardiomyocytes expressing pathologic nuclear lamins.An appraisal of the enzyme stability-activity trade-off.Molecular dynamics simulations of site point mutations in the TPR domain of cyclophilin 40 identify conformational states with distinct dynamic and enzymatic properties.FoldX as Protein Engineering Tool: Better Than Random Based Approaches?Phosphorylation promotes binding affinity of Rap-Raf complex by allosteric modulation of switch loop dynamicsSite-specific amino acid substitution in dodecameric peptides determines the stability and unfolding of c-MYC quadruplex promoting apoptosis in cancer cells
P2860
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P2860
Rigidity versus flexibility: the dilemma of understanding protein thermal stability.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Rigidity versus flexibility: the dilemma of understanding protein thermal stability.
@en
type
label
Rigidity versus flexibility: the dilemma of understanding protein thermal stability.
@en
prefLabel
Rigidity versus flexibility: the dilemma of understanding protein thermal stability.
@en
P2860
P356
P1433
P1476
Rigidity versus flexibility: the dilemma of understanding protein thermal stability.
@en
P2093
Andrey Karshikoff
Rudolf Ladenstein
P2860
P304
P356
10.1111/FEBS.13343
P407
P577
2015-06-13T00:00:00Z