about
Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathwaysRegulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complexPGC-1alpha regulates a HIF2alpha-dependent switch in skeletal muscle fiber typesMeteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesisA PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophyPGC-1alpha negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erb(alpha) axis.Complex regulation of the transactivation function of hypoxia-inducible factor-1 alpha by direct interaction with two distinct domains of the CREB-binding protein/p300.Loss of Pgc-1α expression in aging mouse muscle potentiates glucose intolerance and systemic inflammationRetrograde influence of muscle fibers on their innervation revealed by a novel marker for slow motoneuronsAnti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5.G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophyThe unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1α/ATF6α complexCell-type-specific regulation of degradation of hypoxia-inducible factor 1 alpha: role of subcellular compartmentalization.Separation of the gluconeogenic and mitochondrial functions of PGC-1{alpha} through S6 kinase.Endurance exercise increases skeletal muscle kynurenine aminotransferases and plasma kynurenic acid in humans.Hypoxia-dependent activation of HIF into a transcriptional regulator.Ryanodine receptor fragmentation and sarcoplasmic reticulum Ca2+ leak after one session of high-intensity interval exercise.Modulation of vascular gene expression by hypoxia.Neuronal cholesterol metabolism increases dendritic outgrowth and synaptic markers via a concerted action of GGTase-I and Trk.The transcriptional coactivator PGC-1alpha mediates exercise-induced angiogenesis in skeletal muscle.Human Carboxylesterase 2 Reverses Obesity-Induced Diacylglycerol Accumulation and Glucose Intolerance.Regulation of CDKN2B expression by interaction of Arnt with Miz-1--a basis for functional integration between the HIF and Myc gene regulatory pathways.Intercellular: local and systemic actions of skeletal muscle PGC-1s.The hitchhiker's guide to PGC-1α isoform structure and biological functions.The role of epigenetic modifiers in extended cultures of functional hepatocyte-like cells derived from human neonatal mesenchymal stem cells.Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression.Hypoxia requires notch signaling to maintain the undifferentiated cell state.Role of CBP in regulating HIF-1-mediated activation of transcription.Functional analysis of hypoxia-inducible factor-1 alpha-mediated transactivation. Identification of amino acid residues critical for transcriptional activation and/or interaction with CREB-binding protein.Mechano-signalling pathways in an experimental intensive critical illness myopathy model.Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism.Peroxisome Proliferator-activated Receptor γ Coactivator-1 α Isoforms Selectively Regulate Multiple Splicing Events on Target GenesIdentification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1alpha by the von Hippel-Lindau tumor suppressor gene product.Neurturin is a PGC-1α1-controlled myokine that promotes motor neuron recruitment and neuromuscular junction formation.Kynurenines: Tryptophan's metabolites in exercise, inflammation, and mental health.Inflammation, immunology, stress and depression: a role for kynurenine metabolism in physical exercise and skeletal muscle.The chaperone co-inducer BGP-15 alleviates ventilation-induced diaphragm dysfunction.Small molecule PGC-1α1 protein stabilizers induce adipocyte Ucp1 expression and uncoupled mitochondrial respiration.Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation.Peroxisome proliferator-activated receptor-γ coactivator 1 α1 induces a cardiac excitation-contraction coupling phenotype without metabolic remodelling.
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Jorge L Ruas
@ast
Jorge L Ruas
@en
Jorge L Ruas
@es
Jorge L Ruas
@nl
Jorge L Ruas
@sl
type
label
Jorge L Ruas
@ast
Jorge L Ruas
@en
Jorge L Ruas
@es
Jorge L Ruas
@nl
Jorge L Ruas
@sl
prefLabel
Jorge L Ruas
@ast
Jorge L Ruas
@en
Jorge L Ruas
@es
Jorge L Ruas
@nl
Jorge L Ruas
@sl
P1053
T-3040-2017
P106
P21
P31
P3829
P496
0000-0002-1110-2606