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A new mixed-backbone oligonucleotide against glucosylceramide synthase sensitizes multidrug-resistant tumors to apoptosisEffect of B7.1 costimulation on T-cell based immunity against TAP-negative cancer can be facilitated by TAP1 expressionOlive phenolics as c-Met inhibitors: (-)-Oleocanthal attenuates cell proliferation, invasiveness, and tumor growth in breast cancer modelsGlucosylceramide synthase, a factor in modulating drug resistance, is overexpressed in metastatic breast carcinomaDirect quantitative determination of ceramide glycosylation in vivo: a new approach to evaluate cellular enzyme activity of glucosylceramide synthase.Incorporation of Fluorescence Ceramide-Based HPLC Assay for Rapidly and Efficiently Assessing Glucosylceramide Synthase In Vivo.Direct assessment of P-glycoprotein efflux to determine tumor response to chemotherapy.Biological activities of fusarochromanone: a potent anti-cancer agentCurcumin blocks small cell lung cancer cells migration, invasion, angiogenesis, cell cycle and neoplasia through Janus kinase-STAT3 signalling pathwayEvaluation of anticancer agents using flow cytometry analysis of cancer stem cellsLimited density of an antigen presented by RMA-S cells requires B7-1/CD28 signaling to enhance T-cell immunity at the effector phaseNovel Peptidomimetics for Inhibition of HER2:HER3 Heterodimerization in HER2-Positive Breast CancerDoxorubicin and MBO-asGCS oligonucleotide loaded lipid nanoparticles overcome multidrug resistance in adriamycin resistant ovarian cancer cells (NCI/ADR-RES).The opposite effects of doxorubicin on bone marrow stem cells versus breast cancer stem cells depend on glucosylceramide synthaseCeramide glycosylation by glucosylceramide synthase selectively maintains the properties of breast cancer stem cells.Highly and moderately aggressive mouse ovarian cancer cell lines exhibit differential gene expression.Inhibition of glucosylceramide synthase eliminates the oncogenic function of p53 R273H mutant in the epithelial-mesenchymal transition and induced pluripotency of colon cancer cells.Sphingolipids and expression regulation of genes in cancer.Resuscitating wild-type p53 expression by disrupting ceramide glycosylation: a novel approach to target mutant p53 tumors.3-Ketone-4,6-diene ceramide analogs exclusively induce apoptosis in chemo-resistant cancer cells.Marine natural products-inspired phenylmethylene hydantoins with potent in vitro and in vivo antitumor activities via suppression of Brk and FAK signaling.Curcumin induces small cell lung cancer NCI-H446 cell apoptosis via the reactive oxygen species-mediated mitochondrial pathway and not the cell death receptor pathway.In vivo survivors of transformed mouse ovarian surface epithelial cells display diverse phenotypes for gene expression and tumorigenicity.A role for ceramide in driving cancer cell resistance to doxorubicin.Glucosylceramide synthase blockade down-regulates P-glycoprotein and resensitizes multidrug-resistant breast cancer cells to anticancer drugs.Oligonucleotides blocking glucosylceramide synthase expression selectively reverse drug resistance in cancer cells.Uncoupling ceramide glycosylation by transfection of glucosylceramide synthase antisense reverses adriamycin resistance.Glycosylation of ceramide potentiates cellular resistance to tumor necrosis factor-alpha-induced apoptosis.Expression of glucosylceramide synthase, converting ceramide to glucosylceramide, confers adriamycin resistance in human breast cancer cells.Hepatic regeneration in insulin-like growth factor binding protein-1 transgenic mice.Peptide-based radioimmunoassay for the two isoforms of the human insulin receptor.Taxol-induced ceramide generation and apoptosis in human breast cancer cells.Cellular stress response in Eca-109 cells inhibits apoptosis during early exposure to isorhamnetin.Increased expression of low-affinity insulin receptor isoform and insulin/insulin-like growth factor-I hybrid receptors in term placenta from insulin-resistant women with gestational hypertensionAn N6-methyladenosine at the transited codon 273 of p53 pre-mRNA promotes the expression of R273H mutant protein and drug resistance of cancer cellsCeramide-Rubusoside Nanomicelles, a Potential Therapeutic Approach to Target Cancers Carrying p53 Missense Mutations
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Yong-Yu Liu
@ast
Yong-Yu Liu
@en
Yong-Yu Liu
@es
Yong-Yu Liu
@nl
Yong-Yu Liu
@sl
type
label
Yong-Yu Liu
@ast
Yong-Yu Liu
@en
Yong-Yu Liu
@es
Yong-Yu Liu
@nl
Yong-Yu Liu
@sl
prefLabel
Yong-Yu Liu
@ast
Yong-Yu Liu
@en
Yong-Yu Liu
@es
Yong-Yu Liu
@nl
Yong-Yu Liu
@sl
P106
P1153
26643173400
P31
P496
0000-0002-7968-0162