about
Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent modelsMechanisms of Comorbidities Associated With the Metabolic Syndrome: Insights from the JCR:LA-cp Corpulent Rat StrainCentral and haematopoietic interleukin-1 both contribute to ischaemic brain injury in miceMatrix metalloproteinase-9 and urokinase plasminogen activator mediate interleukin-1-induced neurotoxicityDelayed reperfusion deficits after experimental stroke account for increased pathophysiology.Late-onset epilepsy and occult cerebrovascular diseaseImpaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease.Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitroHigh-fat diet-induced memory impairment in triple-transgenic Alzheimer's disease (3xTgAD) mice is independent of changes in amyloid and tau pathology.Maternal high-fat diet worsens memory deficits in the triple-transgenic (3xTgAD) mouse model of Alzheimer's disease.The role of pro- and antiinflammatory cytokines in neurodegeneration.Interleukin-1 and acute brain injury.Chitinase-like proteins promote IL-17-mediated neutrophilia in a tradeoff between nematode killing and host damage.Brain inflammation is induced by co-morbidities and risk factors for stroke.Interleukin-1 in the brain: mechanisms of action in acute neurodegeneration.Systemic inflammation impairs tissue reperfusion through endothelin-dependent mechanisms in cerebral ischemia.Circulating cytokines and alarmins associated with placental inflammation in high-risk pregnancies.Inflammation in central nervous system injuryAIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3.Experimental intracerebral hemorrhage: avoiding pitfalls in translational research.Neutrophil cerebrovascular transmigration triggers rapid neurotoxicity through release of proteases associated with decondensed DNA.Interleukin-1 and neuronal injury.Delayed administration of interleukin-1 receptor antagonist reduces ischemic brain damage and inflammation in comorbid rats.Translational models for vascular cognitive impairment: a review including larger speciesA quantitative brain map of experimental cerebral malaria pathology.A cross-laboratory preclinical study on the effectiveness of interleukin-1 receptor antagonist in stroke.Efficacy of Alteplase in a Mouse Model of Acute Ischemic Stroke: A Retrospective Pooled Analysis.Systemic inflammation and stroke: aetiology, pathology and targets for therapy.Decreased haemodynamic response and decoupling of cortical gamma-band activity and tissue oxygen perfusion after striatal interleukin-1 injectionSystemic infection, inflammation and acute ischemic stroke.Inflammation and brain injury: acute cerebral ischaemia, peripheral and central inflammation.Mitochondrial Abnormalities and Synaptic Loss Underlie Memory Deficits Seen in Mouse Models of Obesity and Alzheimer's DiseaseThe acute-phase protein PTX3 is an essential mediator of glial scar formation and resolution of brain edema after ischemic injury.Enhanced susceptibility of triple transgenic Alzheimer's disease (3xTg-AD) mice to acute infection.Assessing the contribution of inflammation in models of Alzheimer's disease.Regulation of interleukin-1 in acute brain injury.Interleukin-1 and stroke: biomarker, harbinger of damage, and therapeutic target.Systematic review and meta-analysis of the efficacy of statins in experimental stroke.Systemic immune activation shapes stroke outcome.Interleukin-1 as a pharmacological target in acute brain injury.
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description
hulumtues
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researcher
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wetenschapper
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հետազոտող
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name
Stuart M. Allan
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Stuart M. Allan
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Stuart M. Allan
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Stuart M. Allan
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Stuart M. Allan
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Stuart M. Allan
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Stuart M. Allan
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Stuart M. Allan
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Stuart M. Allan
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Stuart M. Allan
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Stuart M. Allan
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Stuart M. Allan
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Stuart M. Allan
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Stuart M. Allan
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Stuart M. Allan
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P106
P1153
7006687687
P21
P31
P496
0000-0001-9646-4456