Immune-mediated pathology in Duchenne muscular dystrophy.
about
A Novel NF-κB Inhibitor, Edasalonexent (CAT-1004), in Development as a Disease-Modifying Treatment for Patients With Duchenne Muscular Dystrophy: Phase 1 Safety, Pharmacokinetics, and Pharmacodynamics in Adult SubjectsProteomic profiling of mdx-4cv serum reveals highly elevated levels of the inflammation-induced plasma marker haptoglobin in muscular dystrophy.Pharmacological Inhibition of PKCθ Counteracts Muscle Disease in a Mouse Model of Duchenne Muscular Dystrophy.Tissue Tregs.Failure to up-regulate transcription of genes necessary for muscle adaptation underlies limb girdle muscular dystrophy 2A (calpainopathy).Association Study of Exon Variants in the NF-κB and TGFβ Pathways Identifies CD40 as a Modifier of Duchenne Muscular Dystrophy.Spatially localized phosphorous metabolism of skeletal muscle in Duchenne muscular dystrophy patients: 24-month follow-up.Targeting early PKCθ-dependent T-cell infiltration of dystrophic muscle reduces disease severity in a mouse model of muscular dystrophy.Genetic modifiers of Duchenne and facioscapulohumeral muscular dystrophies.Flow Cytometry-Defined CD49d Expression in Circulating T-Lymphocytes Is a Biomarker for Disease Progression in Duchenne Muscular Dystrophy.1 H NMRS of carnosine combined with 31 P NMRS to better characterize skeletal muscle pH dysregulation in Duchenne muscular dystrophy.Proteomic profiling of the dystrophin complex and membrane fraction from dystrophic mdx muscle reveals decreases in the cytolinker desmoglein and increases in the extracellular matrix stabilizers biglycan and fibronectin.Elevated phosphodiester and T2 levels can be measured in the absence of fat infiltration in Duchenne muscular dystrophy patients.Increased Number of Circulating CD8/CD26 T Cells in the Blood of Duchenne Muscular Dystrophy Patients Is Associated with Augmented Binding of Adenosine Deaminase and Higher Muscular Strength Scores.Immunoglobulin therapy ameliorates the phenotype and increases lifespan in the severely affected dystrophin-utrophin double knockout mice.Characterization of the Inflammatory Response in Dystrophic Muscle Using Flow Cytometry.Effect of Ibuprofen on Skeletal Muscle of Dysferlin-null Mice.A cre-inducible DUX4 transgenic mouse model for investigating facioscapulohumeral muscular dystrophy.MicroRNA-206 Downregulation Improves Therapeutic Gene Expression and Motor Function in mdx Mice.Necroptosis mediates myofibre death in dystrophin-deficient miceDrug Repurposing for Duchenne Muscular Dystrophy: The Monoamine Oxidase B Inhibitor Safinamide Ameliorates the Pathological Phenotype in Mice and in Myogenic Cultures From DMD Patients
P2860
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P2860
Immune-mediated pathology in Duchenne muscular dystrophy.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Immune-mediated pathology in Duchenne muscular dystrophy.
@en
type
label
Immune-mediated pathology in Duchenne muscular dystrophy.
@en
prefLabel
Immune-mediated pathology in Duchenne muscular dystrophy.
@en
P2093
P2860
P1476
Immune-mediated pathology in Duchenne muscular dystrophy.
@en
P2093
Amy S Rosenberg
Eric P Hoffman
Janet Woodcock
Lalage M Wakefield
Montserrat Puig
S Armando Villalta
V Ashutosh Rao
P2860
P304
P356
10.1126/SCITRANSLMED.AAA7322
P407
P577
2015-08-01T00:00:00Z