Rapid culling of the CD4+ T cell repertoire in the transition from effector to memory.
about
Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cellsThe Role of Lymphatic Niches in T Cell DifferentiationLower Affinity T Cells are Critical Components and Active Participants of the Immune ResponseDevelopment and Function of Protective and Pathologic Memory CD4 T CellsNarrowing the Gap: Preserving Repertoire Diversity Despite Clonal Selection during the CD4 T Cell ResponseT memory stem cells and HIV: a long-term relationshipT cell chemo-vaccination effects after repeated mucosal SHIV exposures and oral pre-exposure prophylaxisFeedback regulation of proliferation vs. differentiation rates explains the dependence of CD4 T-cell expansion on precursor number.Human naive and memory CD4+ T cell repertoires specific for naturally processed antigens analyzed using libraries of amplified T cells.Coxsackievirus B3 inhibits antigen presentation in vivo, exerting a profound and selective effect on the MHC class I pathway.HIV controller CD4+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity.Dynamic functional modulation of CD4+ T cell recall responses is dependent on the inflammatory environment of the secondary stimulus.Physiological numbers of CD4+ T cells generate weak recall responses following influenza virus challengeElongated TCR alpha chain CDR3 favors an altered CD4 cytokine profile.Epitope density influences CD8+ memory T cell differentiation.Distinct roles of Cdc42 in thymopoiesis and effector and memory T cell differentiationTumor-primed, in vitro-activated CD4+ effector T cells establish long-term memory without exogenous cytokine support or ongoing antigen exposureRepetitive antigen stimulation induces stepwise transcriptome diversification but preserves a core signature of memory CD8(+) T cell differentiation.Impact of distinct poxvirus infections on the specificities and functionalities of CD4+ T cell responsesMemories that last forever: strategies for optimizing vaccine T-cell memory.Low 2-dimensional CD4 T cell receptor affinity for myelin sets in motion delayed response kinetics.Th17 cells are long lived and retain a stem cell-like molecular signatureAntigen affinity and antigen dose exert distinct influences on CD4 T-cell differentiationA peripheral CD4+ T cell precursor for naive, memory, and regulatory T cellsHighly specialized role of Forkhead box O transcription factors in the immune system.High prevalence of low affinity peptide-MHC II tetramer-negative effectors during polyclonal CD4+ T cell responsesImmune mechanisms of HIV control.Antigen-stimulated CD4 T-cell expansion is inversely and log-linearly related to precursor number.High efficiency of antiviral CD4(+) killer T cellsBim mediates the elimination of functionally unfit Th1 responders from the memory pool.Induction and function of virus-specific CD4+ T cell responses.TIM-4, a receptor for phosphatidylserine, controls adaptive immunity by regulating the removal of antigen-specific T cells.Escape from highly effective public CD8+ T-cell clonotypes by HIVVaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infectionType I IFN-dependent T cell activation is mediated by IFN-dependent dendritic cell OX40 ligand expression and is independent of T cell IFNR expression.Bim is required for T-cell allogeneic responses and graft-versus-host disease in vivo.Induction of protective CD4+ T cell-mediated immunity by a Leishmania peptide delivered in recombinant influenza viruses.Phenotype and Hierarchy of Two Transgenic T Cell Lines Targeting the Respiratory Syncytial Virus KdM282-90 Epitope Is Transfer Dose-Dependent.A four-step model for the IL-6 amplifier, a regulator of chronic inflammations in tissue-specific MHC class II-associated autoimmune diseases.Distinct CD4+ helper T cells involved in primary and secondary responses to infection.
P2860
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P2860
Rapid culling of the CD4+ T cell repertoire in the transition from effector to memory.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Rapid culling of the CD4+ T cell repertoire in the transition from effector to memory.
@en
type
label
Rapid culling of the CD4+ T cell repertoire in the transition from effector to memory.
@en
prefLabel
Rapid culling of the CD4+ T cell repertoire in the transition from effector to memory.
@en
P2093
P2860
P1433
P1476
Rapid culling of the CD4+ T cell repertoire in the transition from effector to memory.
@en
P2093
Eugene V Ravkov
Matthew A Williams
Michael J Bevan
P2860
P304
P356
10.1016/J.IMMUNI.2008.02.014
P407
P577
2008-03-20T00:00:00Z