Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle.
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Roles of mTOR Signaling in Brain DevelopmentStochastic model of Tsc1 lesions in mouse brainAdvancing the understanding of autism disease mechanisms through geneticsTiming of mTOR activation affects tuberous sclerosis complex neuropathology in mouse models.A circuitry and biochemical basis for tuberous sclerosis symptoms: from epilepsy to neurocognitive deficitsMechanism-based treatment in tuberous sclerosis complex.The genomic landscape of tuberous sclerosis complexMetabolic requirements for the maintenance of self-renewing stem cells.Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complexTSC1 controls distribution of actin fibers through its effect on function of Rho family of small GTPases and regulates cell migration and polarity.The neural crest lineage as a driver of disease heterogeneity in Tuberous Sclerosis Complex and Lymphangioleiomyomatosis.Metabolic circuits in neural stem cells.Postnatal neurogenesis generates heterotopias, olfactory micronodules and cortical infiltration following single-cell Tsc1 deletion.Tuberous Sclerosis: A New Frontier in Targeted Treatment of AutismImpaired Reelin-Dab1 Signaling Contributes to Neuronal Migration Deficits of Tuberous Sclerosis ComplexPAK2 is an effector of TSC1/2 signaling independent of mTOR and a potential therapeutic target for Tuberous Sclerosis ComplexNewborn cortical neurons: only for neonates?Hypoxia-inducible factor 1a is a Tsc1-regulated survival factor in newborn neurons in tuberous sclerosis complexGlutamine contributes to maintenance of mouse embryonic stem cell self-renewal through PKC-dependent downregulation of HDAC1 and DNMT1/3aTargeted treatment trials for tuberous sclerosis and autism: no longer a dream.Fascin regulates the migration of subventricular zone-derived neuroblasts in the postnatal brain.Genomic analysis of the molecular neuropathology of tuberous sclerosis using a human stem cell model.Expression of Idh1(R132H) in the Murine Subventricular Zone Stem Cell Niche Recapitulates Features of Early Gliomagenesis.Translational research: Rett syndrome and tuberous sclerosis complex.Tuberous sclerosis and epilepsy: role of astrocytes.mTOR signaling in neural stem cells: from basic biology to disease.Evolving neurobiology of tuberous sclerosis complex.Role of the PTEN signaling pathway in autism spectrum disorder.Tuberous Sclerosis Complex: State-of-the-Art Review with a Focus on Pulmonary Involvement.Roles of Diffusion Dynamics in Stem Cell Signaling and Three-Dimensional Tissue Development.TFEB activation restores migration ability to Tsc1-deficient adult neural stem/progenitor cells.A novel mouse model of tuberous sclerosis complex (TSC): eye-specific Tsc1-ablation disrupts visual-pathway development.Tuberous sclerosis complex: From molecular biology to novel therapeutic approaches.Complex Neurological Phenotype in Mutant Mice Lacking Tsc2 in Excitatory Neurons of the Developing Forebrain(123).An overview of therapeutic approaches to brain tumor stem cellsVariation in a range of mTOR-related genes associates with intracranial volume and intellectual disability.Management of CNS-related Disease Manifestations in Patients With Tuberous Sclerosis Complex.TORC1-dependent epilepsy caused by acute biallelic Tsc1 deletion in adult mice.Cell fate decisions: emerging roles for metabolic signals and cell morphology.Glioma.
P2860
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P2860
Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Tsc1 mutant neural stem/progen ...... ions in the lateral ventricle.
@en
type
label
Tsc1 mutant neural stem/progen ...... ions in the lateral ventricle.
@en
prefLabel
Tsc1 mutant neural stem/progen ...... ions in the lateral ventricle.
@en
P2093
P2860
P356
P1433
P1476
Tsc1 mutant neural stem/progen ...... ions in the lateral ventricle.
@en
P2093
Dennis K Burns
Gayatri Shrikhande
Luis F Parada
Renée M McKay
P2860
P304
P356
10.1101/GAD.16750211
P577
2011-08-01T00:00:00Z