GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates.
about
Ret receptor tyrosine kinase sustains proliferation and tissue maturation in intestinal epithelia.Over-production of growth differentiation factor 15 (GDF15) promotes human rhinovirus infection and virus-induced inflammation in the lung.TGF-β contamination of purified recombinant GDF15.Growth differentiation factor 15 mediates epithelial mesenchymal transition and invasion of breast cancers through IGF-1R-FoxM1 signaling.BMPs as new insulin sensitizers: enhanced glucose uptake in mature 3T3-L1 adipocytes via PPARγ and GLUT4 upregulation.Exercise increases circulating GDF15 in humans.Silver linings on the horizon: highlights from the 10th Cachexia Conference.GDF15 and energy balance: homing in on a mechanism.Structure and biophysical characterisation of the human full-length Neurturin-GFRa2 complex - a role for heparan sulfate in signalling.Fasting exacerbates hepatic growth differentiation factor 15 to promote fatty acid β-oxidation and ketogenesis via activating XBP1 signaling in liver.GDF15 promotes the proliferation of cervical cancer cells by phosphorylating AKT1 and Erk1/2 through the receptor ErbB2.New extracellular factors in glioblastoma multiforme development: neurotensin, growth differentiation factor-15, sphingosine-1-phosphate and cytomegalovirus infection.Reduced oxidative capacity in macrophages results in systemic insulin resistance.Moonlighting Activity of Secreted Inflammation-Regulatory Proteins.Binding of EphrinA5 to RET receptor tyrosine kinase: An in vitro study.CRP Stimulates GDF15 Expression in Endothelial Cells through p53.Ret and Substrate-Derived TGF-β Maverick Regulate Space-Filling Dendrite Growth in Drosophila Sensory NeuronsGDF15 Regulates Malat-1 Circular RNA and Inactivates NFκB Signaling Leading to Immune Tolerogenic DCs for Preventing Alloimmune Rejection in Heart TransplantationPathogenesis of Nonalcoholic Steatohepatitis and Hormone-Based Therapeutic ApproachesGDF15 deficiency promotes high fat diet-induced obesity in mice
P2860
0b88efeb991f65ad683da6cff4ece7f3f57e711b1e2e28773371178894a71cb0d9795556acc33897337d5b964e52a96822124e1646d340537b169d723cc566870892a73e16f325163240994155fbe04640905bca6b1075d83cb26b118115c524f17180e44f444936ada51110d76664b632a56dd6e45bab4a7be9daf6adfb5fa6841d0e1a5228f40753026286cc05d3a9d132a9999d21170f2ee2392079a71b69d3e13e9042a58129c8d45fbedc7857e1edf67e69d82525ba4e5cc45cd2d00c01113cec9316f66aeb
P248
Q42377913-99CE4677-9AA8-44C9-8BE5-FA5FA1B398AFQ45323971-3A27EE09-6ADC-48F6-ABBE-6006AA3F83B3Q45826790-7DD927CF-240E-4891-BF37-EEE01EF5E792Q47121253-09178017-E745-4A2F-808C-E0A3D9368EEAQ47141298-C58A558D-F81A-4DC6-95D8-5CF5CA18EE61Q49339915-AA976F76-E86C-4DDF-B967-EB6521A751BBQ49455338-2FC2D5AF-1811-4018-882A-311CF46ADF81Q49557783-5CD9B797-4A05-4CE8-8FFA-B88D389F3FF8Q50134150-75CBA46A-FACC-41CE-93F1-544ADF2457B4Q51246528-6496B466-FA86-4AD7-AFB6-DC84683AAC18Q52326010-B51E41AF-CA6D-43CC-949B-B00127C417A6Q52691329-D9B743B5-6045-4BA1-89A2-2B2A2A70CA0FQ53693528-891C4F1F-FE99-4BFE-9A99-EE54345FE5E9Q54917685-BC5A5A8F-16D1-4D96-83D3-D24C725FFCB3Q54976550-DA1DAA5D-E1AB-4CD8-BD42-908606F345C1Q55486841-4CF4D7A9-0511-491A-8CB1-7CFEA2778C7CQ58696962-BBAE1E9D-FD42-467F-9646-53CD5E1E6DE8Q58697982-F83CE621-6980-43AB-92DB-0DF9904DE8C8Q58705640-BC775AFC-208A-44CD-9A73-4F47A1C4363EQ58803776-7C8F5297-B7C6-4120-816D-FB9B75A9A114
P2860
GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
GFRAL is the receptor for GDF1 ...... in mice and nonhuman primates.
@en
type
label
GFRAL is the receptor for GDF1 ...... in mice and nonhuman primates.
@en
prefLabel
GFRAL is the receptor for GDF1 ...... in mice and nonhuman primates.
@en
P2093
P2860
P921
P356
P1433
P1476
GFRAL is the receptor for GDF1 ...... in mice and nonhuman primates.
@en
P2093
Anthony A Armstrong
Cassandre R Cavanaugh
Chen-Ni Chin
Chichi Huang
Jennifer L Furman
Jose A Chavez
Michael J Hunter
Serena Nelson
Shamina M Rangwala
Shannon E Mullican
P2860
P2888
P356
10.1038/NM.4392
P407
P577
2017-08-28T00:00:00Z