The Groucho/TLE/Grg family of transcriptional co-repressors.
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XIAP monoubiquitylates Groucho/TLE to promote canonical Wnt signalingCell Fate and Differentiation of Bone Marrow Mesenchymal Stem CellsHomeodomain proteins: an updateTargeting the Wnt/β-catenin signaling pathway in liver cancer stem cells and hepatocellular carcinoma cell lines with FH535Evolutionary Adaptation of the Fly Pygo PHD Finger toward Recognizing Histone H3 Tail Methylated at Arginine 2TLE1 function and therapeutic potential in cancerAberrant regulation of Wnt signaling in hepatocellular carcinomaTissue-specific derepression of TCF/LEF controls the activity of the Wnt/β-catenin pathway.A method for WD40 repeat detection and secondary structure prediction.Conditional deletion of N-Myc disrupts neurosensory and non-sensory development of the ear.Cofactor-activated phosphorylation is required for inhibition of cortical neuron differentiation by Groucho/TLE1.The corepressor Tle4 is a novel regulator of murine hematopoiesis and bone development.AES/GRG5: more than just a dominant-negative TLE/GRG family memberCapicua DNA-binding sites are general response elements for RTK signaling in DrosophilaGRG5/AES interacts with T-cell factor 4 (TCF4) and downregulates Wnt signaling in human cells and zebrafish embryos.Origins of context-dependent gene repression by capicua.Degringolade, a SUMO-targeted ubiquitin ligase, inhibits Hairy/Groucho-mediated repression.Dual roles of Oct4 in the maintenance of mouse P19 embryonal carcinoma cells: as negative regulator of Wnt/β-catenin signaling and competence provider for Brachyury induction.The Groucho co-repressor is primarily recruited to local target sites in active chromatin to attenuate transcriptionp15RS/RPRD1A (p15INK4b-related sequence/regulation of nuclear pre-mRNA domain-containing protein 1A) interacts with HDAC2 in inhibition of the Wnt/β-catenin signaling pathway.New insights into the Orange domain of E(spl)-M8, and the roles of the C-terminal domain in autoinhibition and Groucho recruitmentTranscript levels of ten caste-related genes in adult diploid males of Melipona quadrifasciata (Hymenoptera, Apidae) - A comparison with haploid males, queens and workers.Characterization of Aes nuclear foci in colorectal cancer cells.The transcriptional co-repressor Grg3/Tle3 promotes pancreatic endocrine progenitor delamination and β-cell differentiation.The Capicua repressor--a general sensor of RTK signaling in development and disease.Uncovering the pathways underlying whole body regeneration in a chordate model, Botrylloides leachi using de novo transcriptome analysis.Fine-Tuning of the Kaposi's Sarcoma-Associated Herpesvirus Life Cycle in Neighboring Cells through the RTA-JAG1-Notch Pathway.SUMOylated SoxE factors recruit Grg4 and function as transcriptional repressors in the neural crest.Global SUMO Proteome Responses Guide Gene Regulation, mRNA Biogenesis, and Plant Stress Responses.Coordinated Regulation of PPARγ Expression and Activity through Control of Chromatin Structure in Adipogenesis and Obesity.Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.Disrupting Foxh1-Groucho interaction reveals robustness of nodal-based embryonic patterningTLE4 promotes colorectal cancer progression through activation of JNK/c-Jun signaling pathwayDevelopmental Progression in the Coral Acropora digitifera Is Controlled by Differential Expression of Distinct Regulatory Gene NetworksTLE3 as a candidate biomarker of response to taxane therapy.Brinker possesses multiple mechanisms for repression because its primary co-repressor, Groucho, may be unavailable in some cell types.TLE3 represses colorectal cancer proliferation by inhibiting MAPK and AKT signaling pathways.Familial dysautonomia model reveals Ikbkap deletion causes apoptosis of Pax3+ progenitors and peripheral neurons.Suppression of WC-independent frequency transcription by RCO-1 is essential for Neurospora circadian clock.Prolyl isomerase Pin1 and protein kinase HIPK2 cooperate to promote cortical neurogenesis by suppressing Groucho/TLE:Hes1-mediated inhibition of neuronal differentiation.
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The Groucho/TLE/Grg family of transcriptional co-repressors.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
The Groucho/TLE/Grg family of transcriptional co-repressors.
@en
type
label
The Groucho/TLE/Grg family of transcriptional co-repressors.
@en
prefLabel
The Groucho/TLE/Grg family of transcriptional co-repressors.
@en
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P356
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P1476
The Groucho/TLE/Grg family of transcriptional co-repressors.
@en
P2093
Barbara H Jennings
David Ish-Horowicz
P2860
P2888
P356
10.1186/GB-2008-9-1-205
P577
2008-01-31T00:00:00Z
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P6179
1031665811