Mechanisms governing the activation and trafficking of yeast G protein-coupled receptors.
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A microdomain formed by the extracellular ends of the transmembrane domains promotes activation of the G protein-coupled alpha-factor receptorStructure and topology of a peptide segment of the 6th transmembrane domain of the Saccharomyces cerevisae alpha-factor receptor in phospholipid bilayersDominant-negative mutations in the G-protein-coupled alpha-factor receptor map to the extracellular ends of the transmembrane segments.Galpha subunit Gpa2 recruits kelch repeat subunits that inhibit receptor-G protein coupling during cAMP-induced dimorphic transitions in Saccharomyces cerevisiaeInvited review: GPCR structural characterization: Using fragments as building blocks to determine a complete structure.Biosynthesis and biophysical analysis of domains of a yeast G protein-coupled receptor.Identification of a polar region in transmembrane domain 6 that regulates the function of the G protein-coupled alpha-factor receptorIdentifying functionally important conformational changes in proteins: activation of the yeast α-factor receptor Ste2pOligomerization of G-protein-coupled receptors: lessons from the yeast Saccharomyces cerevisiae.Magnificent seven: roles of G protein-coupled receptors in extracellular sensing in fungi.Comparison of class A and D G protein-coupled receptors: common features in structure and activation.The cytoplasmic end of transmembrane domain 3 regulates the activity of the Saccharomyces cerevisiae G-protein-coupled alpha-factor receptorIdentification of destabilizing and stabilizing mutations of Ste2p, a G protein-coupled receptor in Saccharomyces cerevisiae.A WASp-binding type II phosphatidylinositol 4-kinase required for actin polymerization-driven endosome motility.Assessment of constitutive activity of a G protein-coupled receptor, CPR2, in Cryptococcus neoformans by heterologous and homologous methods.The novel ER membrane protein PRO41 is essential for sexual development in the filamentous fungus Sordaria macrospora.A constitutively active GPCR governs morphogenic transitions in Cryptococcus neoformansChemical gradients and chemotropism in yeast.Yeast GPCR signaling reflects the fraction of occupied receptors, not the numberDual lipid modification motifs in G(alpha) and G(gamma) subunits are required for full activity of the pheromone response pathway in Saccharomyces cerevisiae.The C terminus of the Saccharomyces cerevisiae alpha-factor receptor contributes to the formation of preactivation complexes with its cognate G protein.Expression of a G protein-coupled receptor (GPCR) leads to attenuation of signaling by other GPCRs: experimental evidence for a spontaneous GPCR constitutive inactive form.Constitutive internalization of constitutively active agiotensin II AT(1A) receptor mutants is blocked by inverse agonists.Analysis of random PCR-originated mutants of the yeast Ste2 and Ste3 receptors.Oligomerization, biogenesis, and signaling is promoted by a glycophorin A-like dimerization motif in transmembrane domain 1 of a yeast G protein-coupled receptor.A constitutively active GPCR retains its G protein specificity and the ability to form dimers.Identification of residues involved in homodimer formation located within a β-strand region of the N-terminus of a Yeast G protein-coupled receptor.Interacting residues in an activated state of a G protein-coupled receptor.Variable Dependence of Signaling Output on Agonist Occupancy of Ste2p, a G Protein-coupled Receptor in Yeast.A syntaxin homolog encoded by VAM3 mediates down-regulation of a yeast G protein-coupled receptor.
P2860
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P2860
Mechanisms governing the activation and trafficking of yeast G protein-coupled receptors.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Mechanisms governing the activation and trafficking of yeast G protein-coupled receptors.
@en
type
label
Mechanisms governing the activation and trafficking of yeast G protein-coupled receptors.
@en
prefLabel
Mechanisms governing the activation and trafficking of yeast G protein-coupled receptors.
@en
P2860
P356
P1476
Mechanisms governing the activation and trafficking of yeast G protein-coupled receptors
@en
P2093
K J Blumer
M C Overton
P2860
P304
P356
10.1091/MBC.9.4.885
P577
1998-04-01T00:00:00Z