Centrosomes and cancer: revisiting a long-standing relationship.
about
Distinct mechanisms eliminate mother and daughter centrioles in meiosis of starfish oocytes.The PLK4-STIL-SAS-6 module at the core of centriole duplicationTetrahymena Poc1 ensures proper intertriplet microtubule linkages to maintain basal body integrity.Cell-free reconstitution reveals centriole cartwheel assembly mechanisms.SparkText: Biomedical Text Mining on Big Data Framework.Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancerCentriolar CPAP/SAS-4 Imparts Slow Processive Microtubule Growth.Satellite Cells in Muscular Dystrophy - Lost in Polarity.Aurora kinase-induced phosphorylation excludes transcription factor RUNX from the chromatin to facilitate proper mitotic progression.Cep295 is a conserved scaffold protein required for generation of a bona fide mother centrioleQuantitative analysis of human centrosome architecture by targeted proteomics and fluorescence imaging.KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification.Casein kinase II is required for proper cell division and acts as a negative regulator of centrosome duplication in Caenorhabditis elegans embryos.Centriolar SAS-7 acts upstream of SPD-2 to regulate centriole assembly and pericentriolar material formation.A Novel Compound ARN-3236 Inhibits Salt-Inducible Kinase 2 and Sensitizes Ovarian Cancer Cell Lines and Xenografts to Paclitaxel.Centrosomal clustering contributes to chromosomal instability and cancer.Regulation of centriolar satellite integrity and its physiologyHaspin kinase regulates microtubule-organizing center clustering and stability through Aurora kinase C in mouse oocytes.The connections of Wnt pathway components with cell cycle and centrosome: side effects or a hidden logic?Live Imaging of Centriole Dynamics by Fluorescently Tagged Proteins in Starfish Oocyte Meiosis.A cis-eQTL genetic variant of the cancer-testis gene CCDC116 is associated with risk of multiple cancers.Cep78 controls centrosome homeostasis by inhibiting EDD-DYRK2-DDB1VprBP.Disturbed chromosome segregation and multipolar spindle formation in a patient with CHAMP1 mutation.Cdk1 Phosphorylates Drosophila Sas-4 to Recruit Polo to Daughter Centrioles and Convert Them to Centrosomes.The Zebrafish curly fry Is Required for Proper Centrosome and Mitotic Spindle Assembly.The centrosome: a multifaceted cellular weapon against chromosome instability.Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.APC/CFZR-1 Controls SAS-5 Levels To Regulate Centrosome Duplication in Caenorhabditis elegans.Controlling centriole numbers: Geminin family members as master regulators of centriole amplification and multiciliogenesis.Calibrated mitotic oscillator drives motile ciliogenesis.Maintaining centrosomes and cilia.Sequential activities of Dynein, Mud and Asp in centrosome-spindle coupling maintain centrosome number upon mitosis.Phosphorylated Tyr142 β-catenin localizes to centrosomes and is regulated by Syk.Chemical Genetic Screen Identifies Natural Products that Modulate Centriole Number.Interaction between the C. elegans centriolar protein SAS-5 and microtubules facilitates organelle assembly.Once and only once: mechanisms of centriole duplication and their deregulation in disease.Mitotic Nuclear Envelope Breakdown and Spindle Nucleation Are Controlled by Interphase Contacts between Centromeres and the Nuclear Envelope.KAT2-mediated PLK4 acetylation contributes to genomic stability by preserving centrosome number.Colorectal cancer cells require glycogen synthase kinase-3β for sustaining mitosis via translocated promoter region (TPR)-dynein interaction.Structural centrosome aberrations promote non-cell-autonomous invasiveness.
P2860
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P2860
Centrosomes and cancer: revisiting a long-standing relationship.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
Centrosomes and cancer: revisiting a long-standing relationship.
@en
type
label
Centrosomes and cancer: revisiting a long-standing relationship.
@en
prefLabel
Centrosomes and cancer: revisiting a long-standing relationship.
@en
P356
P1476
Centrosomes and cancer: revisiting a long-standing relationship.
@en
P2888
P304
P356
10.1038/NRC3995
P407
P577
2015-10-01T00:00:00Z
P6179
1039571581