Structure-enhanced methods in the development of non-nucleoside inhibitors targeting HIV reverse transcriptase variants.

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Structure-enhanced methods in the development of non-nucleoside inhibitors targeting HIV reverse transcriptase variants.

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2015 nî lūn-bûn

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2015年学术文章

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Structure-enhanced methods in ...... everse transcriptase variants.

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Structure-enhanced methods in ...... everse transcriptase variants.

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Structure-enhanced methods in ...... everse transcriptase variants.

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P1476

Structure-enhanced methods in ...... everse transcriptase variants.

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P2093

Kathleen M Frey

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P2860

Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors

High-resolution structures of HIV-1 reverse transcriptase/TMC278 complexes: strategic flexibility explains potency against resistance mutations.

The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutations

Crystal structures of HIV-1 reverse transcriptase with etravirine (TMC125) and rilpivirine (TMC278): implications for drug design

Lersivirine, a Nonnucleoside Reverse Transcriptase Inhibitor with Activity against Drug-Resistant Human Immunodeficiency Virus Type 1

A comparison of the ability of rilpivirine (TMC278) and selected analogues to inhibit clinically relevant HIV-1 reverse transcriptase mutants

Rational design of potent non-nucleoside inhibitors of HIV-1 reverse transcriptase

Synthesis and biological evaluation of phosphonate analogues of nevirapine

Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

HIV-1 reverse transcriptase and antiviral drug resistance. Part 2.

P304

1767-1772

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scholarly article

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10.2217/FMB.15.122

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2015-10-30T00:00:00Z

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26517310

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Structure-enhanced methods in the development of non-nucleoside inhibitors targeting HIV reverse transcriptase variants.

about

Structure-enhanced methods in the development of non-nucleoside inhibitors targeting HIV reverse transcriptase variants.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698